N-(2-aminoethyl)-6-(di(3-(N-phenylmethoxycarbonyl)-N-(3-(phenylmethoxycarbonylamino)propyl)amino)propyl)aminohexanamide

Base Information

Chemical Name:N-(2-aminoethyl)-6-(di(3-(N-phenylmethoxycarbonyl)-N-(3-(phenylmethoxycarbonylamino)propyl)amino)propyl)aminohexanamide
CAS No.:294864-72-5
Molecular Formula:C₅₂H₇₁N₇O₉
Molecular Weight:938.177
Hs Code.:

Synonyms:N-(2-aminoethyl)-6-(di(3-(N-phenylmethoxycarbonyl)-N-(3-(phenylmethoxycarbonylamino)propyl)amino)propyl)aminohexanamide

Suppliers and Price of N-(2-aminoethyl)-6-(di(3-(N-phenylmethoxycarbonyl)-N-(3-(phenylmethoxycarbonylamino)propyl)amino)propyl)aminohexanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(2-aminoethyl)-6-(di(3-(N-phenylmethoxycarbonyl)-N-(3-(phenylmethoxycarbonylamino)propyl)amino)propyl)aminohexanamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(2-aminoethyl)-6-(di(3-(N-phenylmethoxycarbonyl)-N-(3-(phenylmethoxycarbonylamino)propyl)amino)propyl)aminohexanamide

There total 6 articles about N-(2-aminoethyl)-6-(di(3-(N-phenylmethoxycarbonyl)-N-(3-(phenylmethoxycarbonylamino)propyl)amino)propyl)aminohexanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 294864-71-4
N-(2-(1,1-dimethylethoxycarbonylamino)ethyl-6-(di(3-(N-phenylmethoxycarbonyl)-N-(3-(phenylmethoxycarbonylamino)propyl)amino)propyl)amino)hexanamide

: 294864-72-5
N-(2-aminoethyl)-6-(di(3-(N-phenylmethoxycarbonyl)-N-(3-(phenylmethoxycarbonylamino)propyl)amino)propyl)aminohexanamide

Guidance literature:: With hydrogenchloride; In dichloromethane; for 0.5h;
DOI:10.1016/S0968-0896(00)00113-9

Reference yield:

: 22809-37-6
6-bromohexanoyl chloride

: 294864-72-5
N-(2-aminoethyl)-6-(di(3-(N-phenylmethoxycarbonyl)-N-(3-(phenylmethoxycarbonylamino)propyl)amino)propyl)aminohexanamide

Guidance literature:: Multi-step reaction with 3 steps

1: 68 percent / Et₃N / CH₂Cl₂ / 0 - 20 °C

2: 67 percent / K₂CO₃ / dimethylformamide / 20 h / 85 °C

3: 67 percent / HCl gas / CH₂Cl₂ / 0.5 h

With hydrogenchloride; potassium carbonate; triethylamine; In dichloromethane; N,N-dimethyl-formamide; 1: Acylation / 2: Alkylation / 3: Hydrolysis;
DOI:10.1016/S0968-0896(00)00113-9

Reference yield:

: 4224-70-8
6-bromohexanoic acid

: 294864-72-5
N-(2-aminoethyl)-6-(di(3-(N-phenylmethoxycarbonyl)-N-(3-(phenylmethoxycarbonylamino)propyl)amino)propyl)aminohexanamide

Guidance literature:: Multi-step reaction with 4 steps

1: (COCl)2; DMF / CH₂Cl₂ / 0 - 20 °C

2: 68 percent / Et₃N / CH₂Cl₂ / 0 - 20 °C

3: 67 percent / K₂CO₃ / dimethylformamide / 20 h / 85 °C

4: 67 percent / HCl gas / CH₂Cl₂ / 0.5 h

With hydrogenchloride; oxalyl dichloride; potassium carbonate; triethylamine; N,N-dimethyl-formamide; In dichloromethane; N,N-dimethyl-formamide; 1: Substitution / 2: Acylation / 3: Alkylation / 4: Hydrolysis;
DOI:10.1016/S0968-0896(00)00113-9