alpha-(4-Chlorophenyl)-1H-imidazole-1-ethanol

Base Information

Chemical Name:alpha-(4-Chlorophenyl)-1H-imidazole-1-ethanol
CAS No.:24155-45-1
Molecular Formula:C₁₁H₁₁ClN₂O
Molecular Weight:222.674
Hs Code.:
European Community (EC) Number:246-043-0
DSSTox Substance ID:DTXSID90946983
Nikkaji Number:J86.828K
ChEMBL ID:CHEMBL159785
Mol file:24155-45-1.mol

Synonyms:24155-45-1;EINECS 246-043-0;alpha-(4-Chlorophenyl)-1H-imidazole-1-ethanol;BRN 0524722;Imidazole-1-ethanol, alpha-(p-chlorophenyl)-;N-(beta-(4-Chlorophenyl)-beta-hydroxyethyl)imidazole;Benzyl alcohol, 4-chloro-alpha-(1-imidazolylmethyl)-;1-(4-chlorophenyl)-2-(1H-imidazol-1-yl)ethan-1-ol;CHEMBL159785;SCHEMBL11266884;DTXSID90946983;RF-29;AKOS022307677;LS-78604;1-(4-chlorophenyl)-2-imidazol-1-yl-ethanol;Z280090848

Suppliers and Price of alpha-(4-Chlorophenyl)-1H-imidazole-1-ethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of alpha-(4-Chlorophenyl)-1H-imidazole-1-ethanol

Chemical Property:

Boiling Point:447.2oC at 760 mmHg
Flash Point:224.3oC
PSA：38.05000
Density:1.27g/cm3
LogP:2.27010
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:222.0559907
Heavy Atom Count:15
Complexity:195

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C(CN2C=CN=C2)O)Cl

Technology Process of alpha-(4-Chlorophenyl)-1H-imidazole-1-ethanol

There total 12 articles about alpha-(4-Chlorophenyl)-1H-imidazole-1-ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.1%

: 24155-32-6
1-(4-chlorophenyl)-2-(1H-imidazol-1-yl)ethan-1-one

: 178172-70-8,178172-71-9,24155-45-1
(±)-1-(4-chlorophenyl)-2-(1H-imidazol-1-yl)ethanol

Guidance literature:: With sodium tetrahydroborate; In methanol; for 3h; Cooling with ice; Reflux;

Reference yield: 60.0%

: 288-32-4
1H-imidazole

: 2788-86-5,21019-51-2,53649-47-1,97466-49-4
(2S)-2-(4-chlorophenyl)oxirane

: 24155-45-1
(S)-1-(4-chlorophenyl)-2-(1H-1,3-diazol-1-yl)ethanol

Guidance literature:: In 1,4-dioxane; at 100 ℃; for 24h;
DOI:10.1039/c7ra00083a

Reference yield:

: 536-38-9
4-chlorobenzoylmethyl bromide

: 178172-70-8,178172-71-9,24155-45-1
(±)-1-(4-chlorophenyl)-2-(1H-imidazol-1-yl)ethanol

Guidance literature:: Multi-step reaction with 2 steps

1: CHCl₃ / 0 °C

2: sodium borohydride / ethanol / 4 h / Heating

With sodium tetrahydroborate; In ethanol; chloroform;