3-fluoro-4-[5-fluoro-7-[1-(pyridin-2-ylmethyl)piperidin-4-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino]-N,N-dimethylbenzamide

Base Information

Chemical Name:3-fluoro-4-[5-fluoro-7-[1-(pyridin-2-ylmethyl)piperidin-4-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino]-N,N-dimethylbenzamide
CAS No.:1236281-78-9
Molecular Formula:C₂₆H₂₇F₂N₇O
Molecular Weight:491.543
Hs Code.:

Synonyms:3-fluoro-4-[5-fluoro-7-[1-(pyridin-2-ylmethyl)piperidin-4-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino]-N,N-dimethylbenzamide

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Chemical Property of 3-fluoro-4-[5-fluoro-7-[1-(pyridin-2-ylmethyl)piperidin-4-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino]-N,N-dimethylbenzamide

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Technology Process of 3-fluoro-4-[5-fluoro-7-[1-(pyridin-2-ylmethyl)piperidin-4-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino]-N,N-dimethylbenzamide

There total 1 articles about 3-fluoro-4-[5-fluoro-7-[1-(pyridin-2-ylmethyl)piperidin-4-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino]-N,N-dimethylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 1121-60-4
pyridine-2-carbaldehyde

: 1236284-40-4
3-fluoro-4-[5-fluoro-7-(piperidin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino]-N,N-dimethylbenzamide hydrochloride

: 1236281-78-9
3-fluoro-4-[5-fluoro-7-[1-(pyridin-2-ylmethyl)piperidin-4-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino]-N,N-dimethylbenzamide

Guidance literature:: pyridine-2-carbaldehyde; 3-fluoro-4-[5-fluoro-7-(piperidin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino]-N,N-dimethylbenzamide hydrochloride; With potassium acetate; In dichloromethane; at 20 ℃; for 1h;

With sodium tris(acetoxy)borohydride; In dichloromethane; at 20 ℃;