DL-pentan-2,4-diol

Base Information

• Chemical Name: DL-pentan-2,4-diol
• CAS No.: 1825-14-5
• Molecular Formula: C₅H₁₂O₂
• Molecular Weight: 104.149
• Mol file: 1825-14-5.mol

Synonyms:DL-pentan-2,4-diol

Chemical Property of DL-pentan-2,4-diol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of DL-pentan-2,4-diol

There total 45 articles about DL-pentan-2,4-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2,2,4,6-tetramethyl-[1,3]dioxane (17227-17-7,20268-00-2,20534-56-9) → pentane-1,3-diol (1825-14-5,3950-21-8,36402-52-5,42075-32-1,72345-23-4,625-69-4)

Guidance literature:

With iodine; In water; acetonitrile; at 20 ℃; for 2h;

DOI:10.1016/j.tetlet.2005.10.043

Reference yield: 86.0%

acetylacetone (123-54-6,81235-32-7) → pentane-1,3-diol (1825-14-5,3950-21-8,36402-52-5,42075-32-1,72345-23-4,625-69-4)

Guidance literature:

With sodium tetrahydroborate; In methanol; water;

Reference yield: 78.0%

acetylacetone (123-54-6,81235-32-7) → (+/-)-2-pentanol (6032-29-7,13403-73-1) + 2-Pentanone (107-87-9) + pentane-1,3-diol (1825-14-5,3950-21-8,36402-52-5,42075-32-1,72345-23-4,625-69-4)

Guidance literature:

With samarium diiodide; water; In tetrahydrofuran; at 20 ℃; for 0.141667h;

DOI:10.1248/cpb.53.1017

upstream raw materials:

methyl magnesium iodide

acetaldol

4-hydroxypentan-2-one

acetylacetone

Downstream raw materials:

2,4-bis-phenylcarbamoyloxy-pentane

penta-1,3-diene

2,4-dibromopentane

nitric acid-(1,3-dimethyl-propanediyl ester)

Refernces

• 1、 Jung, Michael E.,Karama, Usama. "Highly diastereoselective Markovnikov hydration of 3,4-dialkoxy-1-alkenes and 4,5-dialkoxy-2-alkenes via a hydroboration-oxidation process". . p. 7907 - 7910. Retrieved 1999.
• 2、 Gordillo, Barbara,Hernandez, Javier. "An alternative strategy for the purification of meso-2,4-pentanediol". . p. 195 - 199. Retrieved 1997.
• 3、 Rust,F.F.,Youngman,E.A.. "-". . p. 3778 - 3781. Retrieved 1962.
• 4、 Kumah, Robert T.,Vijayan, Paranthaman,Ojwach, Stephen O.. "Synthesis and Applications of (Pyridyl)imine Fe(II) Complexes as Catalysts in Transfer Hydrogenation of Ketones". . p. 344 - 352. Retrieved 2020/07/25.
• 5、 -. "Method for preparing beta-diol from beta-diketone". Paragraph 0037; 0048; 0049. . Retrieved 2016/11/24.