[2-((2,2,2-trifluoroethane)thio)ethyl](diphenyl)phosphine

Base Information

• Chemical Name: [2-((2,2,2-trifluoroethane)thio)ethyl](diphenyl)phosphine
• CAS No.: 1209497-11-9
• Molecular Formula: C₁₆H₁₆F₃PS
• Molecular Weight: 328.338
• Mol file: 1209497-11-9.mol

Synonyms:[2-((2,2,2-trifluoroethane)thio)ethyl](diphenyl)phosphine

Chemical Property of [2-((2,2,2-trifluoroethane)thio)ethyl](diphenyl)phosphine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [2-((2,2,2-trifluoroethane)thio)ethyl](diphenyl)phosphine

There total 1 articles about [2-((2,2,2-trifluoroethane)thio)ethyl](diphenyl)phosphine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

2,2,2-trifluoroethanethiol (1544-53-2) + (2-chloroethyl)diphenylphosphane (5055-11-8) → [2-((2,2,2-trifluoroethane)thio)ethyl](diphenyl)phosphine (1209497-11-9)

Guidance literature:

2,2,2-trifluoroethanethiol; With potassium tert-butylate; In acetonitrile; at 20 ℃; for 0.5h;

(2-chloroethyl)diphenylphosphane; In acetonitrile; at 20 ℃; for 48h;

DOI:10.1021/ic901991w

Reference yield:

dichloro( 1,5-cyclooctadiene)platinum(ll) (12080-32-9) + [2-(methylseleno)ethyl](diphenyl)phophine (1209497-10-8) + [2-((2,2,2-trifluoroethane)thio)ethyl](diphenyl)phosphine (1209497-11-9) → [PtCl(κ2-(2-methylselenoethyl)diphenylphosphine)((2-(2,2,2-trifluoroethane)thioethyl)diphenylphosphine)]Cl (1209497-22-2)

Guidance literature:

In dichloromethane; soln. of Ph2PCH2CH2SeMe in CH2Cl2e added dropwise to soln. of Pt complexin CH2Cl2 at room temp.; stirred for 5 min; Ph2PCH2CH2SCH2CF3 in CH2Cl2 added dropwise; 20 min; solvent reduced in vac.; Et2O added; filtered; solid washed with ether; elem. anal.;

DOI:10.1021/ic901991w

Reference yield:

dichloro( 1,5-cyclooctadiene)platinum(ll) (12080-32-9) + [2-((2,2,2-trifluoroethane)thio)ethyl](diphenyl)phosphine (1209497-11-9) + 1-(methylthio)-2-(diphenylphosphino)ethane (20859-51-2) → [PtCl(κ2-(2-methylthioethyl)diphenylphosphine)((2-(2,2,2-trifluoroethane)thioethyl)diphenylphosphine)]Cl (1209497-21-1)

Guidance literature:

In dichloromethane; soln. of Ph2PCH2CH2SMe in CH2Cl2e added dropwise to soln. of Pt complex in CH2Cl2 at room temp.; stirred for 5 min; Ph2PCH2CH2SCH2CF3 in CH2Cl2 added dropwise; 20 min; solvent reduced in vac.; Et2O added; filtered; solid washed with ether; elem. anal.;

DOI:10.1021/ic901991w

upstream raw materials:

2,2,2-trifluoroethanethiol

(2-chloroethyl)diphenylphosphane

Downstream raw materials:

[PtCl(κ2-(2-methylselenoethyl)diphenylphosphine)((2-(2,2,2-trifluoroethane)thioethyl)diphenylphosphine)]Cl

[PtCl(κ2-(2-methylthioethyl)diphenylphosphine)((2-(2,2,2-trifluoroethane)thioethyl)diphenylphosphine)]Cl

Refernces