(3S)-[3-[[imino[[(2,4,6-trimethylphenyl)sulfonyl]amino]methyl]amino]propyl]-1-[(2-nitrophenyl)sulfonyl]-(2R)-vinylaziridine

Base Information

Chemical Name:(3S)-[3-[[imino[[(2,4,6-trimethylphenyl)sulfonyl]amino]methyl]amino]propyl]-1-[(2-nitrophenyl)sulfonyl]-(2R)-vinylaziridine
CAS No.:842166-46-5
Molecular Formula:C₂₃H₂₉N₅O₆S₂
Molecular Weight:535.645
Hs Code.:

Synonyms:(3S)-[3-[[imino[[(2,4,6-trimethylphenyl)sulfonyl]amino]methyl]amino]propyl]-1-[(2-nitrophenyl)sulfonyl]-(2R)-vinylaziridine

Suppliers and Price of (3S)-[3-[[imino[[(2,4,6-trimethylphenyl)sulfonyl]amino]methyl]amino]propyl]-1-[(2-nitrophenyl)sulfonyl]-(2R)-vinylaziridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3S)-[3-[[imino[[(2,4,6-trimethylphenyl)sulfonyl]amino]methyl]amino]propyl]-1-[(2-nitrophenyl)sulfonyl]-(2R)-vinylaziridine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3S)-[3-[[imino[[(2,4,6-trimethylphenyl)sulfonyl]amino]methyl]amino]propyl]-1-[(2-nitrophenyl)sulfonyl]-(2R)-vinylaziridine

There total 8 articles about (3S)-[3-[[imino[[(2,4,6-trimethylphenyl)sulfonyl]amino]methyl]amino]propyl]-1-[(2-nitrophenyl)sulfonyl]-(2R)-vinylaziridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 842166-45-4
[(2S)-hydroxy-(1S)-[3-[[imino[[(2,4,6-trimethylphenyl)sulfonyl]amino]methyl]amino]propyl]but-3-enyl][(2-nitrophenyl)sulfonyl]amine

: 842166-46-5
(3S)-[3-[[imino[[(2,4,6-trimethylphenyl)sulfonyl]amino]methyl]amino]propyl]-1-[(2-nitrophenyl)sulfonyl]-(2R)-vinylaziridine

Guidance literature:: With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; toluene; at 20 ℃; for 0.5h;
DOI:10.1021/jm049429h

Reference yield:

: 68262-71-5,200122-85-6
Boc-Arg(MTS)-OH

: 842166-46-5
(3S)-[3-[[imino[[(2,4,6-trimethylphenyl)sulfonyl]amino]methyl]amino]propyl]-1-[(2-nitrophenyl)sulfonyl]-(2R)-vinylaziridine

Guidance literature:: Multi-step reaction with 6 steps

1: 100 percent / potassium bicarbonate / dimethylformamide / 10 h / 20 °C

2: DIBAL-H / toluene; CH₂Cl₂ / 2 h / -78 °C

3: toluene; CH₂Cl₂; tetrahydrofuran / 6 h / -78 - 0 °C

4: aq. HCl; anisole / dioxane / 2 h / 20 °C

5: 3.2 g / Et₃N; pyridine / CHCl₃ / 12 h / 20 °C

6: 93 percent / PPh₃; diethyl azodicarboxylate / toluene; tetrahydrofuran / 0.5 h / 20 °C

With pyridine; hydrogenchloride; diisobutylaluminium hydride; potassium hydrogencarbonate; methoxybenzene; triethylamine; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; 1,4-dioxane; dichloromethane; chloroform; N,N-dimethyl-formamide; toluene; 6: Mitsunobu reaction;
DOI:10.1021/jm049429h

Reference yield:

: 1694-92-4
2-Nitrobenzenesulfonyl chloride

: 842166-46-5
(3S)-[3-[[imino[[(2,4,6-trimethylphenyl)sulfonyl]amino]methyl]amino]propyl]-1-[(2-nitrophenyl)sulfonyl]-(2R)-vinylaziridine

Guidance literature:: Multi-step reaction with 2 steps

1: 3.2 g / Et₃N; pyridine / CHCl₃ / 12 h / 20 °C

2: 93 percent / PPh₃; diethyl azodicarboxylate / toluene; tetrahydrofuran / 0.5 h / 20 °C

With pyridine; triethylamine; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; chloroform; toluene; 2: Mitsunobu reaction;
DOI:10.1021/jm049429h