Schradan

Base Information

• Chemical Name: Schradan
• CAS No.: 152-16-9
• Molecular Formula: C8H24 N4 O3 P2
• Molecular Weight: 286.251
• Hs Code.: 29299090
• European Community (EC) Number: 205-801-0
• NSC Number: 8929
• UN Number: 3018
• UNII: D77OYM46S1
• DSSTox Substance ID: DTXSID0042373
• Nikkaji Number: J2.967J
• Wikipedia: Schradan
• Wikidata: Q27155770
• Mol file: 152-16-9.mol

Synonyms:octamethyl pyrophosphoramide

Chemical Property of Schradan

Chemical Property:

• Vapor Pressure: 0.000335mmHg at 25°C
• Melting Point: 17℃
• Refractive Index: 1.4698 (589.3 nm 20℃)
• Boiling Point: 319.6°Cat760mmHg
• PKA: 0.85±0.70(Predicted)
• Flash Point: 147.1°C
• PSA: 75.95000
• Density: 1.171g/cm³
• LogP: 1.46560
• XLogP3: -0.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 6
• Exact Mass: 286.13236464
• Heavy Atom Count: 17
• Complexity: 288
• Transport DOT Label: Poison

Purity/Quality:

Schradan ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Toxic by ingestion and inhalation, a cholinesterase inhibitor, use may be restricted.
• Hazard Codes: T+
• Statements: 27/28
• Safety Statements: 36/37-38-45

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Pesticides -> Organophosphate Insecticides
• Canonical SMILES: CN(C)P(=O)(N(C)C)OP(=O)(N(C)C)N(C)C
• Uses: Insecticide.

Technology Process of Schradan

There total 14 articles about Schradan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl N,N,N',N'-tetramethylphosphorodiamidate (2404-65-1) + N,N,N',N'-Tetramethylphosphorodiamidic chloride (1605-65-8) → schradan (152-16-9)

Guidance literature:

With xylene;

DOI:10.1039/jr9500001769

Reference yield:

N,N,N,N,N,N-hexamethylphosphoric triamide (680-31-9) → schradan (152-16-9)

Guidance literature:

With phosphorus pentoxide;

DOI:10.1021/ja01508a011

Reference yield:

N,N,N',N'-Tetramethylphosphorodiamidic chloride (1605-65-8) → schradan (152-16-9)

Guidance literature:

With sodium hydroxide; water; sodium hydrogencarbonate; Reagens 4:Pyridin;

upstream raw materials:

N,N,N,N,N,N-hexamethylphosphoric triamide

methyl-N,N-dimethylphosphoroamidochloridate

triphosphoric acid pentakis-dimethylamide

tetraphosphoric acid hexakis-dimethylamide

Downstream raw materials:

phosphoric acid

dimethyl amine

dimefox

Refernces

• 1、 Toy,Walsh. "". . p. 73,74,76. Retrieved 1963.
• 2、 Gardiner,Kilby. "-". . p. 1769,1770,1772. Retrieved 1950.
• 3、 -. "Alkyl 4-[o-(substituted methyleneamino)-phenyl]-3-thioallophanate miticides and fungicides". . . Retrieved 2008/06/13.
• 4、 -. "Alkyl 4-(o-aminophenyl)-3-thioallophanates". . . Retrieved 2008/06/13.