(2S)-2-[(tert-butoxycarbonyl)amino]-2-methyl-3-(3,4-dimethoxyphenyl)propanoic acid

Base Information

Chemical Name:(2S)-2-[(tert-butoxycarbonyl)amino]-2-methyl-3-(3,4-dimethoxyphenyl)propanoic acid
CAS No.:132970-18-4
Molecular Formula:C₁₇H₂₅NO₆
Molecular Weight:339.389
Hs Code.:

Synonyms:(2S)-2-[(tert-butoxycarbonyl)amino]-2-methyl-3-(3,4-dimethoxyphenyl)propanoic acid

Suppliers and Price of (2S)-2-[(tert-butoxycarbonyl)amino]-2-methyl-3-(3,4-dimethoxyphenyl)propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 3 raw suppliers

Chemical Property of (2S)-2-[(tert-butoxycarbonyl)amino]-2-methyl-3-(3,4-dimethoxyphenyl)propanoic acid

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

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Technology Process of (2S)-2-[(tert-butoxycarbonyl)amino]-2-methyl-3-(3,4-dimethoxyphenyl)propanoic acid

There total 2 articles about (2S)-2-[(tert-butoxycarbonyl)amino]-2-methyl-3-(3,4-dimethoxyphenyl)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 39948-18-0
(S)-3-(3,4-dimethoxyphenyl)-2-methylalanine

: 132970-18-4
(2S)-2-[(tert-butoxycarbonyl)amino]-2-methyl-3-(3,4-dimethoxyphenyl)propanoic acid

Guidance literature:: In dichloromethane; at 20 ℃; for 72h;
DOI:10.1016/j.tetasy.2013.02.007

Reference yield:

: 132970-17-3
2-tert-Butoxycarbonylamino-3-(3,4-dimethoxy-phenyl)-2-methyl-propionic acid methyl ester

: 132970-18-4
Boc-αMeDopa(Me)2

Guidance literature:: With potassium hydroxide; In 1,4-dioxane; at 60 ℃; for 48h; Yield given;
DOI:10.1055/s-1991-26380

Reference yield: 89.0%

: 132970-18-4
(2S)-2-[(tert-butoxycarbonyl)amino]-2-methyl-3-(3,4-dimethoxyphenyl)propanoic acid

: 1428736-38-2
(2S)-2-[(tert-butoxycarbonyl)amino]-2-methyl-3-(3,4-dimethoxyphenyl)propanamide

Guidance literature:: (2S)-2-[(tert-butoxycarbonyl)amino]-2-methyl-3-(3,4-dimethoxyphenyl)propanoic acid; With chloroformic acid ethyl ester; triethylamine; In dichloromethane; at 0 ℃; for 0.116667h;

With ammonia; In dichloromethane; deuteromethanol; at 20 ℃; for 96h;
DOI:10.1016/j.tetasy.2013.02.007