1-{3-(benzyloxy)-5-[(1-methyl-1H-pyrazol-3-yl)carbamoyl]phenoxy}cyclobutane carboxylic acid

Base Information

Chemical Name:1-{3-(benzyloxy)-5-[(1-methyl-1H-pyrazol-3-yl)carbamoyl]phenoxy}cyclobutane carboxylic acid
CAS No.:1310807-62-5
Molecular Formula:C₂₃H₂₃N₃O₅
Molecular Weight:421.453
Hs Code.:

Synonyms:1-{3-(benzyloxy)-5-[(1-methyl-1H-pyrazol-3-yl)carbamoyl]phenoxy}cyclobutane carboxylic acid

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Chemical Property of 1-{3-(benzyloxy)-5-[(1-methyl-1H-pyrazol-3-yl)carbamoyl]phenoxy}cyclobutane carboxylic acid

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Technology Process of 1-{3-(benzyloxy)-5-[(1-methyl-1H-pyrazol-3-yl)carbamoyl]phenoxy}cyclobutane carboxylic acid

There total 3 articles about 1-{3-(benzyloxy)-5-[(1-methyl-1H-pyrazol-3-yl)carbamoyl]phenoxy}cyclobutane carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1310809-42-7
C₂₅H₂₇N₃O₅

: 1310807-62-5
1-{3-(benzyloxy)-5-[(1-methyl-1H-pyrazol-3-yl)carbamoyl]phenoxy}cyclobutane carboxylic acid

Guidance literature:: C₂₅H₂₇N₃O₅; With sodium hydroxide; In ethanol; water; at 20 ℃; for 4h;

With hydrogenchloride; In water;

Reference yield:

: 35120-18-4
ethyl 1-bromocyclobutane-1-carboxylate

: 1310807-62-5
1-{3-(benzyloxy)-5-[(1-methyl-1H-pyrazol-3-yl)carbamoyl]phenoxy}cyclobutane carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 35 h / 80 - 120 °C

2: sodium hydroxide / ethanol; water / 4 h / 20 °C

With potassium carbonate; sodium hydroxide; In ethanol; water; N,N-dimethyl-formamide;

Reference yield:

: 915771-04-9
3-hydroxy-N-(1-methyl-1H-pyrazol-3-yl)-5-[(phenylmethyl)oxy]benzamide

: 1310807-62-5
1-{3-(benzyloxy)-5-[(1-methyl-1H-pyrazol-3-yl)carbamoyl]phenoxy}cyclobutane carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 35 h / 80 - 120 °C

2: sodium hydroxide / ethanol; water / 4 h / 20 °C

With potassium carbonate; sodium hydroxide; In ethanol; water; N,N-dimethyl-formamide;