Technology Process of 1-{7-[3-(benzyloxycarbonyl)propyl]-1,2,3,4-tetrahydro-1(R,S)-naphthyl}-2,3,4-tri-O-benzyl-α-L-fucopyranose
There total 7 articles about 1-{7-[3-(benzyloxycarbonyl)propyl]-1,2,3,4-tetrahydro-1(R,S)-naphthyl}-2,3,4-tri-O-benzyl-α-L-fucopyranose which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
4 A molecular sieve; tetraethylammonium bromide;
In
dichloromethane;
at 20 ℃;
for 24h;
DOI:10.1016/S0968-0896(98)80017-5
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 82 percent / triethylamine / PdCl2(PPh3)2 / dimethylformamide / 70 °C
2: 96 percent / H2 / Pd-C / ethanol / 1 h
3: 61 percent / H2SO4; CrO3 / H2O; acetone / 2.5 h
4: 88 percent / DCC; DMAP / CH2Cl2 / 18 h
5: 79 percent / sodium borohydride / methanol / 1 h
6: 42 percent / tetraethylammonium bromide; 4 Angstroem molecular sieves / CH2Cl2 / 24 h / 20 °C
With
chromium(VI) oxide; dmap; sodium tetrahydroborate; 4 A molecular sieve; sulfuric acid; tetraethylammonium bromide; hydrogen; triethylamine; dicyclohexyl-carbodiimide;
bis-triphenylphosphine-palladium(II) chloride; palladium on activated charcoal;
In
methanol; ethanol; dichloromethane; water; N,N-dimethyl-formamide; acetone;
1: Condensation / 2: Catalytic hydrogenation / 3: Oxidation / 4: Esterification / 5: Reduction / 6: Condensation;
DOI:10.1016/S0968-0896(98)80017-5
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 96 percent / H2 / Pd-C / ethanol / 1 h
2: 61 percent / H2SO4; CrO3 / H2O; acetone / 2.5 h
3: 88 percent / DCC; DMAP / CH2Cl2 / 18 h
4: 79 percent / sodium borohydride / methanol / 1 h
5: 42 percent / tetraethylammonium bromide; 4 Angstroem molecular sieves / CH2Cl2 / 24 h / 20 °C
With
chromium(VI) oxide; dmap; sodium tetrahydroborate; 4 A molecular sieve; sulfuric acid; tetraethylammonium bromide; hydrogen; dicyclohexyl-carbodiimide;
palladium on activated charcoal;
In
methanol; ethanol; dichloromethane; water; acetone;
1: Catalytic hydrogenation / 2: Oxidation / 3: Esterification / 4: Reduction / 5: Condensation;
DOI:10.1016/S0968-0896(98)80017-5
