S-methyl O-benzyl carbonothioate

Base Information

• Chemical Name: S-methyl O-benzyl carbonothioate
• CAS No.: 22426-83-1
• Molecular Formula: C₉H₁₀O₂S
• Molecular Weight: 182.243
• Mol file: 22426-83-1.mol

Synonyms:S-methyl O-benzyl carbonothioate

Chemical Property of S-methyl O-benzyl carbonothioate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of S-methyl O-benzyl carbonothioate

There total 5 articles about S-methyl O-benzyl carbonothioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

carbon monoxide (201230-82-2) + benzyl alcohol (100-51-6,185532-71-2) + methyl iodide (74-88-4) → S-methyl O-benzyl carbonothioate (22426-83-1)

Guidance literature:

carbon monoxide; benzyl alcohol; With sulfur; 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; at 80 ℃; for 6h; under 7500.6 Torr;

methyl iodide; In tetrahydrofuran; at 20 ℃; for 16h; under 750.06 Torr;

DOI:10.1016/S0040-4020(02)01331-5

Reference yield: 87.0%

carbon oxide sulfide (463-58-1) + benzyl alcohol (100-51-6,185532-71-2) + methyl iodide (74-88-4) → S-methyl O-benzyl carbonothioate (22426-83-1)

Guidance literature:

carbon oxide sulfide; benzyl alcohol; With 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; at 20 ℃; for 1h; under 750.06 Torr;

methyl iodide; In tetrahydrofuran; at 20 ℃; for 2h; under 750.06 Torr;

DOI:10.1016/S0040-4020(02)01331-5

Reference yield:

Thiocarbonic acid O-benzyl ester (125178-42-9) + methyl iodide (74-88-4) → S-methyl O-benzyl carbonothioate (22426-83-1)

Guidance literature:

In tetrahydrofuran; at 20 ℃; for 16h; under 750.06 Torr;

DOI:10.1016/S0040-4039(02)01834-8

upstream raw materials:

carbon oxide sulfide

benzyl alcohol

methyl iodide

carbon monoxide

Downstream raw materials:

benzyl chloroformate

Refernces

• 1、 Mizuno, Takumi,Takahashi, Junko,Ogawa, Akiya. "Benzyl chloroformate (CbzCl) synthesis using carbon monoxide as a carbonyl source". . p. 10011 - 10015. Retrieved 2007/10/03.
• 2、 Kapadia,Shukla,Bose,Fujiwara,Lloyd. "Revised structure of paederoside, a novel monoterpene S-methyl thiocarbonate". . p. 1937 - 1938. Retrieved 2007/10/11.