C₂₇H₁₈N₄O₄

Base Information

• Chemical Name: C₂₇H₁₈N₄O₄
• CAS No.: 1622051-84-6
• Molecular Formula: C₂₇H₁₈N₄O₄
• Molecular Weight: 462.464
• Mol file: 1622051-84-6.mol

Synonyms:C₂₇H₁₈N₄O₄

Chemical Property of C₂₇H₁₈N₄O₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of C₂₇H₁₈N₄O₄

There total 2 articles about C₂₇H₁₈N₄O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

2-(2-nitrophenyl)-1H-pyrrole (1245720-73-3) + benzaldehyde (100-52-7) → C27H18N4O4 (1622051-84-6)

Guidance literature:

2-(2-nitrophenyl)-1H-pyrrole; benzaldehyde; With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 11h; Inert atmosphere; Schlenk technique;

With chloranil; In dichloromethane; at 20 ℃; Inert atmosphere; Schlenk technique;

DOI:10.1002/ejoc.201402446

Reference yield:

2-nitrophenyl bromide (577-19-5) → C27H18N4O4 (1622051-84-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: caesium carbonate / acetonitrile / 72 h / Reflux; Inert atmosphere; Schlenk technique

2.1: trifluoroacetic acid / dichloromethane / 11 h / 20 °C / Inert atmosphere; Schlenk technique

2.2: 20 °C / Inert atmosphere; Schlenk technique

With caesium carbonate; trifluoroacetic acid; In dichloromethane; acetonitrile;

DOI:10.1002/ejoc.201402446

Reference yield: 78.0%

C27H18N4O4 (1622051-84-6) → C27H22N4 (1622051-86-8)

Guidance literature:

With palladium 10% on activated carbon; hydrazine hydrate; In ethanol; Reflux; Inert atmosphere; Schlenk technique;

DOI:10.1002/ejoc.201402446

upstream raw materials:

2-nitrophenyl bromide

2-(2-nitrophenyl)-1H-pyrrole

benzaldehyde

Downstream raw materials:

C₂₇H₂₂N₄