2,2'-(4-Aminophenylimino)diethanol

Base Information

• Chemical Name: 2,2'-(4-Aminophenylimino)diethanol
• CAS No.: 7575-35-1
• Molecular Formula: C10H16N2O2
• Molecular Weight: 196.249
• Hs Code.: 2922199090
• European Community (EC) Number: 231-473-3
• UNII: O0618TXU5S
• DSSTox Substance ID: DTXSID9043805
• Nikkaji Number: J231.963B
• Wikidata: Q27285149
• ChEMBL ID: CHEMBL1626089
• Mol file: 7575-35-1.mol

Synonyms:2,2'-((4-aminophenyl)imino)bis(ethanol);4-APE;BHEPDA;N,N-bis(2-hydroxyethyl)-1,4-phenylenediamine;N,N-bis(2-hydroxyethyl)-p-phenylenediamine;N,N-bis-(2-hydroxyethyl)-4-phenylenediamine;N,N-bis-(2-hydroxyethyl)-4-phenylenediamine dihydrochloride;N,N-bis-(2-hydroxyethyl)-4-phenylenediamine monohydrochloride;N,N-bis-(2-hydroxyethyl)-4-phenylenediamine sulfate;N,N-bis-(2-hydroxyethyl)-4-phenylenediamine sulfate (1:1);N,N-bis-(2-hydroxyethyl)-4-phenylenediamine sulfate (2:1)

Chemical Property of 2,2'-(4-Aminophenylimino)diethanol

Chemical Property:

• Melting Point: 87-88 °C
• Boiling Point: 416.4 °C at 760 mmHg
• PKA: 14.40±0.10(Predicted)
• Flash Point: 205.6 °C
• PSA: 69.72000
• Density: 1.244 g/cm³
• LogP: 0.64100
• XLogP3: 0
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 196.121177757
• Heavy Atom Count: 14
• Complexity: 141

Purity/Quality:

98%Min ^*data from raw suppliers

2-[(4-Amino-phenyl)-(2-hydroxy-ethyl)-amino]-ethanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1N)N(CCO)CCO

Technology Process of 2,2'-(4-Aminophenylimino)diethanol

There total 5 articles about 2,2'-(4-Aminophenylimino)diethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

N,N-bis(2-hydroxyethyl)-4-nitroaniline (18226-17-0) → N,N-bis(2-hydroxyethyl)-4-aminoaniline (7575-35-1)

Guidance literature:

With hydrogenchloride; tin(ll) chloride; In water; for 1h; Heating;

DOI:10.1016/j.bmc.2003.10.057

Reference yield:

4-chlorobenzonitrile (100-00-5) → N,N-bis(2-hydroxyethyl)-4-aminoaniline (7575-35-1)

Guidance literature:

Multi-step reaction with 2 steps

2: H₂ / Pd-C / ethanol

With hydrogen; palladium on activated charcoal; In ethanol;

DOI:10.1021/ja01493a036

Reference yield:

2,2'-(phenylimino)bis[ethanol] (120-07-0) → p-nitroso-N,N-bis(β-hydroxy-ethyl)aniline (3590-52-1) + N,N-bis(2-hydroxyethyl)-4-aminoaniline (7575-35-1)

Guidance literature:

With sodium nitrite; In hydrogenchloride; water;

upstream raw materials:

N,N-bis(2-hydroxyethyl)-4-nitroaniline

4-Fluoronitrobenzene

4-chlorobenzonitrile

2,2'-(phenylimino)bis[ethanol]

Downstream raw materials:

C₁₈H₂₂N₂O₃

C₁₈H₂₀ClN₃O₄

C₁₈H₂₀ClN₃O₄

C₁₇H₂₀N₄O₄