Ethanol, 2,2'-[(4-nitrophenyl)imino]bis-

Base Information

• Chemical Name: Ethanol, 2,2'-[(4-nitrophenyl)imino]bis-
• CAS No.: 18226-17-0
• Molecular Formula: C10H14 N2 O4
• Molecular Weight: 226.232
• Hs Code.: 2922199090
• European Community (EC) Number: 242-104-0
• NSC Number: 523436
• UNII: 9TAJ327HG4
• DSSTox Substance ID: DTXSID3066340
• Nikkaji Number: J266.062H
• Wikidata: Q81992941
• ChEMBL ID: CHEMBL19407
• Mol file: 18226-17-0.mol

Synonyms:18226-17-0;N-(4-Nitrophenyl)diethanolamine;2,2'-((4-Nitrophenyl)azanediyl)diethanol;Ethanol, 2,2'-[(4-nitrophenyl)imino]bis-;N,N-Bis(2-hydroxyethyl)-4-nitroaniline;2-[N-(2-hydroxyethyl)-4-nitroanilino]ethanol;2,2'-(4-nitrophenylazanediyl)diethanol;N,N-Bis(2-hydroxyethyl)-p-nitroaniline;N,N-Bis(2-hydroxyethyl)-p-nitrileaniline;2,2'-((4-Nitrophenyl)imino)bis(ethanol);Ethanol, 2,2'-((p-nitrophenyl)imino)di-;9TAJ327HG4;Ethanol, 2,2'-((4-nitrophenyl)imino)bis-;EINECS 242-104-0;MFCD00047726;NSC 523436;NSC-523436;2,2'-((4-Nitrophenyl)imino)bisethanol;2,2/'-[(4-nitrophenyl)imino]bisethanol;2,2'-[(4-NITROPHENYL)IMINO]BISETHANOL;2-[(2-hydroxyethyl)(4-nitrophenyl)amino]ethan-1-ol;2,2'-[(4-Nitrophenyl)imino]bis(ethanol);2,2'-[(4-nitrophenyl)imino]diethanol;NSC523436;UNII-9TAJ327HG4;Oprea1_149237;CHEMBL19407;SCHEMBL168393;DTXSID3066340;SCHEMBL18077349;ADAL1025864;2,2'-(4-Nitrophenylimino)diethanol;AKOS010483935;Ethanol,2'-[(p-nitrophenyl)imino]di-;Ethanol,2'-[(4-nitrophenyl)imino]bis-;NS-02842;2-[(2-hydroxyethyl)-4-nitroanilino]ethanol;CS-0212304;4-[n,n-bis(2-hydroxyethyl)amino]nitrobenzene;2-((Hydroxyethyl)(4-nitrophenyl)amino)ethan-1-ol;A880911;AA-504/06585004;2-[(2-hydroxyethyl)-(4-nitrophenyl)-amino]-ethanol

Chemical Property of Ethanol, 2,2'-[(4-nitrophenyl)imino]bis-

Chemical Property:

• Melting Point: 101-102 °C
• Boiling Point: 451.7°Cat760mmHg
• PKA: 14.15±0.10(Predicted)
• Flash Point: 227°C
• PSA: 89.52000
• Density: 1.352g/cm³
• LogP: 0.90900
• Storage Temp.: 2-8°C
• XLogP3: 0.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 5
• Exact Mass: 226.09535693
• Heavy Atom Count: 16
• Complexity: 205

Purity/Quality:

97% ^*data from raw suppliers

2,2'-((4-Nitrophenyl)azanediyl)diethanol 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1N(CCO)CCO)[N+](=O)[O-]

Technology Process of Ethanol, 2,2'-[(4-nitrophenyl)imino]bis-

There total 10 articles about Ethanol, 2,2'-[(4-nitrophenyl)imino]bis- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

2,2'-iminobis[ethanol] (111-42-2) + 4-Fluoronitrobenzene (350-46-9,178603-76-4) → N,N-bis(2-hydroxyethyl)-4-nitroaniline (18226-17-0)

Guidance literature:

In dimethyl sulfoxide; for 3.5h; Heating;

DOI:10.1016/j.bmc.2003.10.057

Reference yield: 86.0%

4-nitro-aniline (100-01-6,104810-17-5) + 2-chloro-ethanol (107-07-3) → N,N-bis(2-hydroxyethyl)-4-nitroaniline (18226-17-0)

Guidance literature:

With potassium carbonate; In ethanol; for 4h; Reflux;

DOI:10.1039/c8tb00546j

Reference yield: 75.0%

4-chlorobenzonitrile (100-00-5) + 2,2'-iminobis[ethanol] (111-42-2) → N,N-bis(2-hydroxyethyl)-4-nitroaniline (18226-17-0)

Guidance literature:

at 120 ℃; for 6h;

DOI:10.1021/acs.orglett.5b00131

upstream raw materials:

oxirane

4-nitro-aniline

4-chlorobenzonitrile

2,2'-iminobis[ethanol]

Downstream raw materials:

bis(2-chloroethyl)(4-nitrophenyl)amine

N,N-bis<2-<(methylsulfonyl)oxy>ethyl>-4-nitroaniline

4-Nitro-[N,N-bis(2-acetoxyethyl)]aniline

N,N-bis(2-chloroethyl)-N'-acetyl-1,4-phenylenediamine