N₁-(4-chlorophenyl)-N₁-[2-(4-chlorophenyl)-2-oxoethyl]-2-phenylacetamide

Base Information

Chemical Name:N₁-(4-chlorophenyl)-N₁-[2-(4-chlorophenyl)-2-oxoethyl]-2-phenylacetamide
CAS No.:705972-09-4
Molecular Formula:C₂₂H₁₇Cl₂NO₂
Molecular Weight:398.288
Hs Code.:

N<sub>1</sub>-(4-chlorophenyl)-N<sub>1</sub>-[2-(4-chlorophenyl)-2-oxoethyl]-2-phenylacetamide

Synonyms:N₁-(4-chlorophenyl)-N₁-[2-(4-chlorophenyl)-2-oxoethyl]-2-phenylacetamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N₁-(4-chlorophenyl)-N₁-[2-(4-chlorophenyl)-2-oxoethyl]-2-phenylacetamide

Chemical Property:

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Technology Process of N₁-(4-chlorophenyl)-N₁-[2-(4-chlorophenyl)-2-oxoethyl]-2-phenylacetamide

There total 3 articles about N₁-(4-chlorophenyl)-N₁-[2-(4-chlorophenyl)-2-oxoethyl]-2-phenylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 35755-44-3
1-(4-chlorophenyl)-2-[(4-chlorophenyl)amino]ethan-1-one

: 103-80-0
phenylacetyl chloride

: 705972-09-4
N₁-(4-chlorophenyl)-N₁-[2-(4-chlorophenyl)-2-oxoethyl]-2-phenylacetamide

Guidance literature:: In tetrahydrofuran; at 25 ℃; for 2h;
DOI:10.1016/j.tet.2004.03.036

Reference yield:

: 106-47-8
4-chloro-aniline

: 705972-09-4
N₁-(4-chlorophenyl)-N₁-[2-(4-chlorophenyl)-2-oxoethyl]-2-phenylacetamide

Guidance literature:: Multi-step reaction with 2 steps

1: 77 percent / NaHCO₃ / ethanol / 6 h / 25 °C

2: 64 percent / tetrahydrofuran / 2 h / 25 °C

With sodium hydrogencarbonate; In tetrahydrofuran; ethanol;
DOI:10.1016/j.tet.2004.03.036

Reference yield:

: 536-38-9
4-chlorobenzoylmethyl bromide

: 705972-09-4
N₁-(4-chlorophenyl)-N₁-[2-(4-chlorophenyl)-2-oxoethyl]-2-phenylacetamide

Guidance literature:: Multi-step reaction with 2 steps

1: 77 percent / NaHCO₃ / ethanol / 6 h / 25 °C

2: 64 percent / tetrahydrofuran / 2 h / 25 °C

With sodium hydrogencarbonate; In tetrahydrofuran; ethanol;
DOI:10.1016/j.tet.2004.03.036