2'-O-acetyl-5'-O-benzoyl-3'-O-tetrahydrofuranyl-O⁴-methyl-6,3'-methanouridine

Base Information

Chemical Name:2'-O-acetyl-5'-O-benzoyl-3'-O-tetrahydrofuranyl-O⁴-methyl-6,3'-methanouridine
CAS No.:115848-02-7
Molecular Formula:C₂₄H₂₆N₂O₉
Molecular Weight:486.478
Hs Code.:

2'-O-acetyl-5'-O-benzoyl-3'-O-tetrahydrofuranyl-O<sup>4</sup>-methyl-6,3'-methanouridine

Synonyms:2'-O-acetyl-5'-O-benzoyl-3'-O-tetrahydrofuranyl-O⁴-methyl-6,3'-methanouridine

Suppliers and Price of 2'-O-acetyl-5'-O-benzoyl-3'-O-tetrahydrofuranyl-O⁴-methyl-6,3'-methanouridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2'-O-acetyl-5'-O-benzoyl-3'-O-tetrahydrofuranyl-O⁴-methyl-6,3'-methanouridine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2'-O-acetyl-5'-O-benzoyl-3'-O-tetrahydrofuranyl-O⁴-methyl-6,3'-methanouridine

There total 11 articles about 2'-O-acetyl-5'-O-benzoyl-3'-O-tetrahydrofuranyl-O⁴-methyl-6,3'-methanouridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 1191-99-7,75454-45-4
2,3-dihydro-2H-furan

: 103931-50-6
2'-O-acetyl-5'-O-benzoyl-O⁴-methyl-6,3'-methanouridine

: 115848-02-7
2'-O-acetyl-5'-O-benzoyl-3'-O-tetrahydrofuranyl-O⁴-methyl-6,3'-methanouridine

Guidance literature:: With toluene-4-sulfonic acid; In 1,4-dioxane; Ambient temperature;
DOI:10.1248/cpb.36.162

Reference yield:

: 7781-23-9
2,4-dimethoxy-6-methylpyrimidine

: 115848-02-7
2'-O-acetyl-5'-O-benzoyl-3'-O-tetrahydrofuranyl-O⁴-methyl-6,3'-methanouridine

Guidance literature:: Multi-step reaction with 7 steps

1: 1.) n-BuLi / 1.) THF/n-hexane, -35 deg C, 1 h, 2.) THF, -35 deg C, 1 h

2: tetrabutylammonium fluoride / tetrahydrofuran / 0.17 h / Ambient temperature

3: pyridine / Ambient temperature

4: 90 percent trifluoroacetic acid / 1.5 h / Ambient temperature

5: Et₃N / CH₂Cl₂ / 2 h

6: 82 percent / stannic chloride / acetonitrile / 3 h / Ambient temperature

7: 82 percent / p-toluenesulfonic acid / dioxane / Ambient temperature

With pyridine; n-butyllithium; tetrabutyl ammonium fluoride; tin(IV) chloride; toluene-4-sulfonic acid; triethylamine; trifluoroacetic acid; In tetrahydrofuran; 1,4-dioxane; dichloromethane; acetonitrile;
DOI:10.1248/cpb.36.162

Reference yield:

: 98-88-4
benzoyl chloride

: 115848-02-7
2'-O-acetyl-5'-O-benzoyl-3'-O-tetrahydrofuranyl-O⁴-methyl-6,3'-methanouridine

Guidance literature:: Multi-step reaction with 5 steps

1: pyridine / Ambient temperature

2: 90 percent trifluoroacetic acid / 1.5 h / Ambient temperature

3: Et₃N / CH₂Cl₂ / 2 h

4: 82 percent / stannic chloride / acetonitrile / 3 h / Ambient temperature

5: 82 percent / p-toluenesulfonic acid / dioxane / Ambient temperature

With pyridine; tin(IV) chloride; toluene-4-sulfonic acid; triethylamine; trifluoroacetic acid; In 1,4-dioxane; dichloromethane; acetonitrile;
DOI:10.1248/cpb.36.162