Pheanthine

Base Information

Chemical Name:Pheanthine
CAS No.:1263-79-2
Molecular Formula:C₃₈H₄₂N₂O₆
Molecular Weight:622.761
Hs Code.:
NSC Number:105130
UNII:DDW9ZLW86P
DSSTox Substance ID:DTXSID101317023
Nikkaji Number:J563.881J
Wikidata:Q27276343
Metabolomics Workbench ID:134304
ChEMBL ID:CHEMBL445477
Mol file:1263-79-2.mol

Synonyms:(+)-tetrandrine;(+-)-tetrandrine;(-)-tetrandrine;(R,S)-Tetrandrine;(S,S)-tetrandrine;6,6',7,12-tetramethoxy-2,2'-dimethyl-(1beta)-berbaman;d-tetrandrine;DL-tetrandrine;hanjisong;isotetrandrine;isotetrandrine dihydrochloride;L-tetrandrine;NSC-77037;phaeanthine;tetrandrine;tetrandrine dihydrochloride;tetrandrine dihydrochloride, (1beta)-isomer;tetrandrine, (1'beta)-isomer

Suppliers and Price of Pheanthine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AHH
L-Tetrandrine 98%
10g
$ 730.00

Total 33 raw suppliers

Chemical Property of Pheanthine

Chemical Property:

Melting Point:210°
Boiling Point:710.5oC at 760 mmHg
Flash Point:175.8oC
PSA：61.86000
Density:1.172g/cm3
LogP:7.03820
XLogP3:6.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:4
Exact Mass:622.30428706
Heavy Atom Count:46
Complexity:979

Purity/Quality:

99% ^*data from raw suppliers

L-Tetrandrine 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)OC)OC
Isomeric SMILES:CN1CCC2=CC(=C3C=C2[C@H]1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)C[C@@H]6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)OC)OC

Technology Process of Pheanthine

There total 37 articles about Pheanthine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.2%

: C₃₈H₄₃BrN₂O₆

: 477-57-6,518-34-3,1263-79-2,23495-89-8,23495-90-1,26137-48-4,26695-12-5,5990-67-0
tetrandrine

Guidance literature:: With copper(l) iodide; caesium carbonate; In N,N-dimethyl-formamide; for 60h; Reagent/catalyst; Solvent; Reflux; Inert atmosphere;

Reference yield:

: dehatrine

: 477-57-6,518-34-3,1263-79-2,23495-89-8,23495-90-1,26137-48-4,26695-12-5,5990-67-0
(+)-isotetrandrine

Guidance literature:: Multi-step reaction with 2 steps

1: 58 mg / NaBH₄ / methanol / Ambient temperature

2: 1.) 35percent HCHO; 2.) NaBH₄ / 1.) MeOH, room temp., 10 min; 2.) MeOH, room temp., 2 h

With sodium tetrahydroborate; formaldehyd; In methanol;
DOI:10.1016/0031-9422(89)80062-7

Reference yield:

: 1472-62-4
N-methylcoclaurine

: 477-57-6,518-34-3,1263-79-2,23495-89-8,23495-90-1,26137-48-4,26695-12-5,5990-67-0
(+)-isotetrandrine

Guidance literature:: With tartaric acid; In water; for 168h; biosynthesis with young branches of Cocculus laurifolius DC;
DOI:10.1016/0040-4020(80)80107-4