Ephedrine, m-hydroxy-

Base Information

Chemical Name:Ephedrine, m-hydroxy-
CAS No.:65133-68-8
Molecular Formula:C₁₀H₁₅NO₂
Molecular Weight:181.235
Hs Code.:
UNII:8CO60645ZS
Wikidata:Q27896026
ChEMBL ID:CHEMBL2068767

Synonyms:Ephedrine, m-hydroxy-;8CO60645ZS;UNII-8CO60645ZS;65133-68-8;(aR)-alpha-[(1S)-1-Aminoethyl]-3-hydroxybenzenemethanol;Benzenemethanol, 3-hydroxy-alpha-((1S)-1-(methylamino)ethyl)-, (alphaR)-;Benzenemethanol, 3-hydroxy-alpha-(1-(methylamino)ethyl)-, (R-(R*,S*))-;CHEMBL2068767;SCHEMBL13158609;Q27896026;BENZENEMETHANOL, 3-HYDROXY-.ALPHA.-((1S)-1-(METHYLAMINO)ETHYL)-, (.ALPHA.R)-;BENZENEMETHANOL, 3-HYDROXY-.ALPHA.-(1-(METHYLAMINO)ETHYL)-, (R-(R*,S*))-

Suppliers and Price of Ephedrine, m-hydroxy-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Ephedrine, m-hydroxy-

Chemical Property:

XLogP3:0.6
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:181.110278721
Heavy Atom Count:13
Complexity:152

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C(C1=CC(=CC=C1)O)O)NC
Isomeric SMILES:C[C@@H]([C@@H](C1=CC(=CC=C1)O)O)NC

Technology Process of Ephedrine, m-hydroxy-

There total 9 articles about Ephedrine, m-hydroxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: (1R,2S)-1-(meta-hydroxyphenyl)-2-benzyloxycarbonylamino-1-propanol

: 65133-68-8
[11C]-m-hydroxyephedrine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; for 6h; Heating;
DOI:10.1002/(SICI)1099-1344(200005)43:6<603::AID-JLCR345>3.0.CO;2-#

Reference yield:

: 54-49-9,61-59-6,4956-27-8,7619-17-2,19289-78-2,21480-43-3,21480-44-4,46064-19-1,73952-03-1
(1R,2S)-metaraminol

: 65133-68-8
[11C]-m-hydroxyephedrine

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / Na₂CO₃ / H₂O; diethyl ether / 18 h / 20 °C

2: 80 percent / LiAlH₄ / tetrahydrofuran / 6 h / Heating

With lithium aluminium tetrahydride; sodium carbonate; In tetrahydrofuran; diethyl ether; water; 1: Substitution / 2: Reduction;
DOI:10.1002/(SICI)1099-1344(200005)43:6<603::AID-JLCR345>3.0.CO;2-#