ethyl 2-methyl-2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]propanoate

Base Information

Chemical Name:ethyl 2-methyl-2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]propanoate
CAS No.:1146546-99-7
Molecular Formula:C₁₈H₂₇BO₅
Molecular Weight:334.22
Hs Code.:

Synonyms:ethyl 2-methyl-2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]propanoate

Suppliers and Price of ethyl 2-methyl-2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 3 raw suppliers

Chemical Property of ethyl 2-methyl-2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]propanoate

Chemical Property:

Purity/Quality:: 97% ^*data from raw suppliers

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Technology Process of ethyl 2-methyl-2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]propanoate

There total 5 articles about ethyl 2-methyl-2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 59227-80-4
2-(4-bromophenoxy)-2-methylpropanoic acid ethyl ester

: 73183-34-3
bis(pinacol)diborane

: 1146546-99-7
ethyl 2-methyl-2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]propanoate

Guidance literature:: With potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In dimethyl sulfoxide; at 100 ℃;

Reference yield: 87.0%

: 76-09-5
2,3-dimethyl-2,3-butane diol

: 13675-18-8
tetrahydroxydiboron

: 637-07-0
Clofibrate

: 1146546-99-7
ethyl 2-methyl-2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]propanoate

Guidance literature:: tetrahydroxydiboron; Clofibrate; With methanesulfonic acid(2-dicyclohexylphosphino-2′,4′,6′-triisopropyl-1,1′-biphenyl)[2-(2′-amino-1,1′-biphenyl)]palladium(II); potassium acetate; XPhos; In ethanol; at 80 ℃; for 4h; Inert atmosphere; Schlenk technique;

2,3-dimethyl-2,3-butane diol; In dichloromethane; at 20 ℃; for 8h; Inert atmosphere; Schlenk technique;
DOI:10.1002/anie.201813708

Reference yield: 51.0%

: 637-07-0
Clofibrate

: 73183-34-3
bis(pinacol)diborane

: 1146546-99-7
ethyl 2-methyl-2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]propanoate

Guidance literature:: With pyridine-4-carbonitrile; potassium phosphate; sodium oxalate; 2,4,5-tri(9H-carbazol-9-yl)-6-(ethyl(phenyl)amino)isophthalonitrile; In acetonitrile; at 20 ℃; for 24h; Irradiation; Inert atmosphere; Sealed tube;
DOI:10.1021/jacs.1c05994