4-fluoro-3,5-dimethylphenyl acetate

Base Information

• Chemical Name: 4-fluoro-3,5-dimethylphenyl acetate
• CAS No.: 1043450-64-1
• Molecular Formula: C₁₀H₁₁FO₂
• Molecular Weight: 182.195
• Mol file: 1043450-64-1.mol

Synonyms:4-fluoro-3,5-dimethylphenyl acetate

Chemical Property of 4-fluoro-3,5-dimethylphenyl acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 4-fluoro-3,5-dimethylphenyl acetate

There total 2 articles about 4-fluoro-3,5-dimethylphenyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-fluoro-m-xylene (443-88-9) + 2-(diacetoxyiodo)mesitylene (33035-41-5) → 4-fluoro-3,5-dimethylphenyl acetate (1043450-64-1) + 3-fluoro-2,4-dimethylphenyl acetate

Guidance literature:

With acridine; palladium diacetate; In acetic anhydride; acetic acid; at 100 ℃; for 16h; Reagent/catalyst; Overall yield = 28 %; Overall yield = 55 %Chromat.;

DOI:10.1021/ol4024248

Reference yield:

2-fluoro-m-xylene (443-88-9) + [bis(acetoxy)iodo]benzene (3240-34-4) → 4-fluoro-3,5-dimethylphenyl acetate (1043450-64-1) + 3-fluoro-2,4-dimethylphenyl acetate

Guidance literature:

With palladium diacetate; In acetic anhydride; acetic acid; at 100 ℃; Overall yield = 42 %Chromat.;

DOI:10.1021/ol4024248

Reference yield:

4-fluoro-3,5-dimethylphenyl acetate (1043450-64-1) → 4-fluoro-3,5-dimethylphenol (1043450-63-0)

Guidance literature:

4-fluoro-3,5-dimethylphenyl acetate; With potassium hydroxide; water; In 1,4-dioxane; at 25 ℃; for 0.5h;

With hydrogenchloride; In 1,4-dioxane; water;

upstream raw materials:

2-fluoro-m-xylene

2-(diacetoxyiodo)mesitylene

[bis(acetoxy)iodo]benzene

Downstream raw materials:

4-fluoro-3,5-dimethylphenol