methyl 2,6-di-O-benzyl-3,4-O-isopropylidene-1-thio-β-D-galactopyranoside

Base Information

Chemical Name:methyl 2,6-di-O-benzyl-3,4-O-isopropylidene-1-thio-β-D-galactopyranoside
CAS No.:113421-41-3
Molecular Formula:C₂₄H₃₀O₅S
Molecular Weight:430.565
Hs Code.:

Synonyms:methyl 2,6-di-O-benzyl-3,4-O-isopropylidene-1-thio-β-D-galactopyranoside

Suppliers and Price of methyl 2,6-di-O-benzyl-3,4-O-isopropylidene-1-thio-β-D-galactopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of methyl 2,6-di-O-benzyl-3,4-O-isopropylidene-1-thio-β-D-galactopyranoside

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 2,6-di-O-benzyl-3,4-O-isopropylidene-1-thio-β-D-galactopyranoside

There total 5 articles about methyl 2,6-di-O-benzyl-3,4-O-isopropylidene-1-thio-β-D-galactopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.6%

: 55663-79-1
methyl 3,4-O-isopropylidene-1-thio-β-D-galactopyranoside

: 100-39-0
benzyl bromide

: 113421-41-3
methyl 2,6-di-O-benzyl-3,4-O-isopropylidene-1-thio-β-D-galactopyranoside

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 12h;
DOI:10.1016/0008-6215(88)84110-7

Reference yield:

: 55722-48-0
methyl 2,3,4,6-tetra-O-acetyl-1-thio-β-D-galactopyranoside

: 113421-41-3
methyl 2,6-di-O-benzyl-3,4-O-isopropylidene-1-thio-β-D-galactopyranoside

Guidance literature:: Multi-step reaction with 3 steps

1: 82 percent / NaOMe / methanol / 1.) 20 deg C, 10 min; 2.) 0-4 deg C, 12 h

2: 1.) Et₃N; 2.) aq. trifluoroacetic acid (50percent) / 1.) TsOH*H₂O / 1.) 20 deg C, 12 h; 2.) CH₂Cl₂, 20 deg C, 15 min

3: 90.6 percent / NaH / dimethylformamide / 12 h / 20 °C

With sodium methylate; sodium hydride; triethylamine; trifluoroacetic acid; toluene-4-sulfonic acid; In methanol; N,N-dimethyl-formamide;
DOI:10.1016/0008-6215(88)84110-7

Reference yield:

: 4163-60-4
β-D-galactose peracetate

: 113421-41-3
methyl 2,6-di-O-benzyl-3,4-O-isopropylidene-1-thio-β-D-galactopyranoside

Guidance literature:: Multi-step reaction with 4 steps

1: 89.2 percent / molecular sieves (4A) / boron trifluoride etherate (BF₃*Et₂O) / CH₂Cl₂ / 1.) 20 deg C, 2 h; 2.) 0-5 deg C, 48 h

2: 82 percent / NaOMe / methanol / 1.) 20 deg C, 10 min; 2.) 0-4 deg C, 12 h

3: 1.) Et₃N; 2.) aq. trifluoroacetic acid (50percent) / 1.) TsOH*H₂O / 1.) 20 deg C, 12 h; 2.) CH₂Cl₂, 20 deg C, 15 min

4: 90.6 percent / NaH / dimethylformamide / 12 h / 20 °C

With 4 A molecular sieve; sodium methylate; sodium hydride; triethylamine; trifluoroacetic acid; boron trifluoride diethyl etherate; toluene-4-sulfonic acid; In methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/0008-6215(88)84110-7