Technology Process of (R)-2-Phenyl-2-ethylglutaric acid
There total 10 articles about (R)-2-Phenyl-2-ethylglutaric acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium hydroxide;
In
ethanol;
for 4h;
Heating;
DOI:10.1021/jo00122a064
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 95 percent / H2 / 5percent Pd/C / ethanol
2: 89 percent / aq. NaOH / ethanol / 4 h / Heating
With
sodium hydroxide; hydrogen;
palladium on activated charcoal;
In
ethanol;
DOI:10.1021/jo00122a064
- Guidance literature:
-
Multi-step reaction with 10 steps
1: 20 percent / D-glucose, bakers' yeast / aq. ethanol / 16 h / 23 °C / bakers' yeastY
2: 76 percent / LiBH4 / tetrahydrofuran / 5 - 10 °C
3: 73 percent / H5IO6 / tetrahydrofuran / 0.17 h
4: 75 percent / CHCl3 / 1 h / Ambient temperature
5: H2 / 5percent Pd/C / ethanol
6: HCl / ethanol
7: 73 percent / PCC
8: 61 percent / Me3Al, Zn / tetrahydrofuran; hexane / 1 h / 0 °C
9: 95 percent / H2 / 5percent Pd/C / ethanol
10: 89 percent / aq. NaOH / ethanol / 4 h / Heating
With
hydrogenchloride; sodium hydroxide; lithium borohydride; D-glucose; bakers' yeast; hydrogen; trimethylaluminum; periodic acid; pyridinium chlorochromate; zinc;
palladium on activated charcoal;
In
tetrahydrofuran; ethanol; hexane; chloroform;
DOI:10.1021/jo00122a064
