(R)-Diethyl 2-phenyl-2-ethylglutarate

Base Information

Chemical Name:(R)-Diethyl 2-phenyl-2-ethylglutarate
CAS No.:170450-72-3
Molecular Formula:C₁₇H₂₄O₄
Molecular Weight:292.375
Hs Code.:

Synonyms:(R)-Diethyl 2-phenyl-2-ethylglutarate

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Chemical Property of (R)-Diethyl 2-phenyl-2-ethylglutarate

Chemical Property:

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Technology Process of (R)-Diethyl 2-phenyl-2-ethylglutarate

There total 9 articles about (R)-Diethyl 2-phenyl-2-ethylglutarate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 170450-71-2
(R)-Diethyl 2-phenyl-2-vinylglutarate

: 170450-72-3
(R)-Diethyl 2-phenyl-2-ethylglutarate

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol;
DOI:10.1021/jo00122a064

Reference yield:

: 170450-69-8
(S)-Diethyl 2-phenyl-2-(hydroxymethyl)glutarate

: 170450-72-3
(R)-Diethyl 2-phenyl-2-ethylglutarate

Guidance literature:: Multi-step reaction with 3 steps

1: 73 percent / PCC

2: 61 percent / Me₃Al, Zn / tetrahydrofuran; hexane / 1 h / 0 °C

3: 95 percent / H₂ / 5percent Pd/C / ethanol

With hydrogen; trimethylaluminum; pyridinium chlorochromate; zinc; palladium on activated charcoal; In tetrahydrofuran; ethanol; hexane;
DOI:10.1021/jo00122a064

Reference yield:

: 170450-70-1
(S)-Diethyl 2-phenyl-2-formylglutarate

: 170450-72-3
(R)-Diethyl 2-phenyl-2-ethylglutarate

Guidance literature:: Multi-step reaction with 2 steps

1: 61 percent / Me₃Al, Zn / tetrahydrofuran; hexane / 1 h / 0 °C

2: 95 percent / H₂ / 5percent Pd/C / ethanol

With hydrogen; trimethylaluminum; zinc; palladium on activated charcoal; In tetrahydrofuran; ethanol; hexane;
DOI:10.1021/jo00122a064