1-(2,5-dimethyl-1H-pyrrol-1-yl)-4''-nitro-4,1':4',1''-terphenylene

Base Information

• Chemical Name: 1-(2,5-dimethyl-1H-pyrrol-1-yl)-4''-nitro-4,1':4',1''-terphenylene
• CAS No.: 936217-16-2
• Molecular Formula: C₂₄H₂₀N₂O₂
• Molecular Weight: 368.435
• Mol file: 936217-16-2.mol

Synonyms:1-(2,5-dimethyl-1H-pyrrol-1-yl)-4''-nitro-4,1':4',1''-terphenylene

Chemical Property of 1-(2,5-dimethyl-1H-pyrrol-1-yl)-4''-nitro-4,1':4',1''-terphenylene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(2,5-dimethyl-1H-pyrrol-1-yl)-4''-nitro-4,1':4',1''-terphenylene

There total 3 articles about 1-(2,5-dimethyl-1H-pyrrol-1-yl)-4''-nitro-4,1':4',1''-terphenylene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

4-(2,5-dimethyl-1H-pyrrol-1-yl)-4'-bromobiphenyl (936217-13-9) + 4-nitrophenylboronic acid (24067-17-2) → 1-(2,5-dimethyl-1H-pyrrol-1-yl)-4''-nitro-4,1':4',1''-terphenylene (936217-16-2)

Guidance literature:

With cesium fluoride; tetrakis-(triphenylphosphino)-palladium⁽⁰⁾; In tetrahydrofuran; for 30h; Heating;

DOI:10.1055/s-2007-965891

Reference yield:

4-Bromophenylboronic acid (5467-74-3) → 1-(2,5-dimethyl-1H-pyrrol-1-yl)-4''-nitro-4,1':4',1''-terphenylene (936217-16-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 98 percent / cesium fluoride / tetrakis(triphenylphosphino)palladium / tetrahydrofuran / 15 h / Heating

2: 46 percent / cesium fluoride / tetrakis(triphenylphosphino)palladium / tetrahydrofuran / 30 h / Heating

With cesium fluoride; tetrakis-(triphenylphosphino)-palladium⁽⁰⁾; In tetrahydrofuran; 1: Suzuki cross-coupling reaction / 2: Suzuki cross-coupling reaction;

DOI:10.1055/s-2007-965891

Reference yield:

1-(2,5-dimethyl-1H-pyrrol-1-yl)-4-iodobenzene (288608-09-3) → 1-(2,5-dimethyl-1H-pyrrol-1-yl)-4''-nitro-4,1':4',1''-terphenylene (936217-16-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 98 percent / cesium fluoride / tetrakis(triphenylphosphino)palladium / tetrahydrofuran / 15 h / Heating

2: 46 percent / cesium fluoride / tetrakis(triphenylphosphino)palladium / tetrahydrofuran / 30 h / Heating

With cesium fluoride; tetrakis-(triphenylphosphino)-palladium⁽⁰⁾; In tetrahydrofuran; 1: Suzuki cross-coupling reaction / 2: Suzuki cross-coupling reaction;

DOI:10.1055/s-2007-965891

upstream raw materials:

4-(2,5-dimethyl-1H-pyrrol-1-yl)-4'-bromobiphenyl

4-nitrophenylboronic acid

4-Bromophenylboronic acid

1-(2,5-dimethyl-1H-pyrrol-1-yl)-4-iodobenzene