Technology Process of (((4-bromobut-2-yn-1-yl)oxy)methyl)benzene
There total 3 articles about (((4-bromobut-2-yn-1-yl)oxy)methyl)benzene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
carbon tetrabromide; triphenylphosphine;
In
dichloromethane;
at 0 - 20 ℃;
for 2.5h;
DOI:10.1039/c1cc11351h
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: n-butyllithium / tetrahydrofuran; hexane / 0.17 h / -78 °C / Inert atmosphere
1.2: 2 h / -78 - 20 °C / Inert atmosphere
1.3: Inert atmosphere
2.1: carbon tetrabromide; triphenylphosphine / dichloromethane / 2.5 h / 0 - 20 °C
With
n-butyllithium; carbon tetrabromide; triphenylphosphine;
In
tetrahydrofuran; hexane; dichloromethane;
DOI:10.1039/c1cc11351h
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: tetra-(n-butyl)ammonium iodide; sodium hydride / tetrahydrofuran / 0.33 h / 0 °C / Inert atmosphere
1.2: 0 - 20 °C / Inert atmosphere
2.1: n-butyllithium / tetrahydrofuran; hexane / 0.17 h / -78 °C / Inert atmosphere
2.2: 2 h / -78 - 20 °C / Inert atmosphere
2.3: Inert atmosphere
3.1: carbon tetrabromide; triphenylphosphine / dichloromethane / 2.5 h / 0 - 20 °C
With
n-butyllithium; carbon tetrabromide; tetra-(n-butyl)ammonium iodide; sodium hydride; triphenylphosphine;
In
tetrahydrofuran; hexane; dichloromethane;
DOI:10.1039/c1cc11351h
