methyl 2-acetamido-2-deoxy-3-O-benzyl-4-O-(3,4,6-tri-O-benzyl-β-D-galactopyranosyl)-2',6-di-O-(methane-1,2-diyl)-β-D-glucopyranoside

Base Information

Chemical Name:methyl 2-acetamido-2-deoxy-3-O-benzyl-4-O-(3,4,6-tri-O-benzyl-β-D-galactopyranosyl)-2',6-di-O-(methane-1,2-diyl)-β-D-glucopyranoside
CAS No.:440345-52-8
Molecular Formula:C₄₄H₅₁NO₁₁
Molecular Weight:769.889
Hs Code.:

Synonyms:methyl 2-acetamido-2-deoxy-3-O-benzyl-4-O-(3,4,6-tri-O-benzyl-β-D-galactopyranosyl)-2',6-di-O-(methane-1,2-diyl)-β-D-glucopyranoside

Suppliers and Price of methyl 2-acetamido-2-deoxy-3-O-benzyl-4-O-(3,4,6-tri-O-benzyl-β-D-galactopyranosyl)-2',6-di-O-(methane-1,2-diyl)-β-D-glucopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 2-acetamido-2-deoxy-3-O-benzyl-4-O-(3,4,6-tri-O-benzyl-β-D-galactopyranosyl)-2',6-di-O-(methane-1,2-diyl)-β-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 2-acetamido-2-deoxy-3-O-benzyl-4-O-(3,4,6-tri-O-benzyl-β-D-galactopyranosyl)-2',6-di-O-(methane-1,2-diyl)-β-D-glucopyranoside

There total 11 articles about methyl 2-acetamido-2-deoxy-3-O-benzyl-4-O-(3,4,6-tri-O-benzyl-β-D-galactopyranosyl)-2',6-di-O-(methane-1,2-diyl)-β-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 108-24-7
acetic anhydride

: (2R,3S,4S,4aR,8aR,10R,11R,12R,12aS,13aS)-3,4,12-Tris-benzyloxy-2-benzyloxymethyl-10-methoxy-decahydro-1,5,7,9,13-pentaoxa-dibenzo[a,d]cyclononen-11-ylamine

: 440345-52-8
methyl 2-acetamido-2-deoxy-3-O-benzyl-4-O-(3,4,6-tri-O-benzyl-β-D-galactopyranosyl)-2',6-di-O-(methane-1,2-diyl)-β-D-glucopyranoside

Guidance literature:: With pyridine; at 20 ℃; for 16h;
DOI:10.1021/ja0169771

Reference yield:

: 440345-53-9
methyl 2-azido-3-O-benzyl-2-deoxy-β-D-glucopyranoside

: 440345-52-8
methyl 2-acetamido-2-deoxy-3-O-benzyl-4-O-(3,4,6-tri-O-benzyl-β-D-galactopyranosyl)-2',6-di-O-(methane-1,2-diyl)-β-D-glucopyranoside

Guidance literature:: Multi-step reaction with 7 steps

1.1: 98 percent / imidazole / dimethylformamide / 2 h / 0 °C

2.1: 80 percent / BF₃*Et₂O / CH₂Cl₂ / 3 h / -40 °C

3.1: 95 percent / 48percent aq. tetrafluoroboric acid / acetonitrile / 0.08 h / 20 °C

4.1: 98 percent / NaOMe; MeOH / 48 h / 20 °C

5.1: CH₂Cl₂; acetonitrile / 1 h / 20 °C

5.2: 60 percent / N-iodosuccinimide; trifluoromethanesulfonic acid / acetonitrile; CH₂Cl₂ / 2 h / -35 °C

6.1: 89 percent / 1,3-propanedithiol; Et₃N; pyridine / H₂O / 6 h / 20 °C

7.1: 98 percent / pyridine / 16 h / 20 °C

With pyridine; 1H-imidazole; 1.3-propanedithiol; methanol; boron trifluoride diethyl etherate; sodium methylate; triethylamine; In dichloromethane; water; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/ja0169771

Reference yield:

: 440345-54-0
methyl 2-azido-3-O-benzyl-2-deoxy-4,6-O-benzylidine-D-glucopyranoside

: 440345-52-8
methyl 2-acetamido-2-deoxy-3-O-benzyl-4-O-(3,4,6-tri-O-benzyl-β-D-galactopyranosyl)-2',6-di-O-(methane-1,2-diyl)-β-D-glucopyranoside

Guidance literature:: Multi-step reaction with 8 steps

1.1: 85 percent / tetrafluoroboronic acid / CH₂Cl₂ / 1 h

2.1: 98 percent / imidazole / dimethylformamide / 2 h / 0 °C

3.1: 80 percent / BF₃*Et₂O / CH₂Cl₂ / 3 h / -40 °C

4.1: 95 percent / 48percent aq. tetrafluoroboric acid / acetonitrile / 0.08 h / 20 °C

5.1: 98 percent / NaOMe; MeOH / 48 h / 20 °C

6.1: CH₂Cl₂; acetonitrile / 1 h / 20 °C

6.2: 60 percent / N-iodosuccinimide; trifluoromethanesulfonic acid / acetonitrile; CH₂Cl₂ / 2 h / -35 °C

7.1: 89 percent / 1,3-propanedithiol; Et₃N; pyridine / H₂O / 6 h / 20 °C

8.1: 98 percent / pyridine / 16 h / 20 °C

With pyridine; 1H-imidazole; 1.3-propanedithiol; methanol; tetrafluoroboric acid; boron trifluoride diethyl etherate; sodium methylate; triethylamine; In dichloromethane; water; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/ja0169771