2-Chlorodiphenyl ether

Base Information

• Chemical Name: 2-Chlorodiphenyl ether
• CAS No.: 2689-07-8
• Molecular Formula: C12H9ClO
• Molecular Weight: 204.656
• Hs Code.: 2909309090
• Mol file: 2689-07-8.mol

Synonyms:Ether,o-chlorophenyl phenyl (6CI,7CI,8CI);1-Chloro-2-phenoxybenzene;2-Chlorodiphenyl ether;2-Chlorophenyl phenyl ether;NSC 39654;PCDE 1;o-Chlorodiphenyl ether;o-Chlorodiphenyl oxide;o-Chlorophenyl phenyl ether;

Chemical Property of 2-Chlorodiphenyl ether

Chemical Property:

• Appearance/Colour: yellowish solid
• Melting Point: 24-26oC
• Boiling Point: 267.1 °C at 760 mmHg
• Flash Point: 118.7 °C
• PSA: 9.23000
• Density: 1.19 g/cm³
• LogP: 4.13230

Purity/Quality:

97% ^*data from raw suppliers

1-Chloro-2-phenoxybenzene 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Chlorodiphenyl ether

There total 12 articles about 2-Chlorodiphenyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2-monochlorophenol (95-57-8) + phenylboronic acid (98-80-6) → 2-chlorodiphenyl ether (2689-07-8)

Guidance literature:

With copper diacetate; 4 A molecular sieve; triethylamine; In dichloromethane; at 25 ℃; for 18h;

DOI:10.1016/S0040-4039(98)00502-4

Reference yield: 90.0%

iodobenzene (591-50-4) + 2-monochlorophenol (95-57-8) → 2-chlorodiphenyl ether (2689-07-8)

Guidance literature:

With sodium hydroxide; In neat (no solvent); at 90 ℃; for 6h; Green chemistry;

DOI:10.1007/s10562-019-03070-5

Reference yield: 87.0%

C7H7O3S(1-)*C15H15ClIO3(1+) + phenol (108-95-2,27073-41-2) → 2-chlorodiphenyl ether (2689-07-8)

Guidance literature:

With potassium carbonate; In toluene; at 55 ℃; for 2h; Sealed tube;

DOI:10.1002/adsc.201901187

upstream raw materials:

2-iodochlorobenzene

potassium phenolate

2-phenoxyaniline

bromobenzene

Downstream raw materials:

o-Phenoxyphenol

4-(2'-chlorophenoxy)acetophenone

3-<4-(2-chlorophenoxy)benzoyl>acrylic acid

4-(2-chlorophenoxy)phenacyl chloride