1,2-diamino-3-chloro-pyrazinium mesitylenate

Base Information

• Chemical Name: 1,2-diamino-3-chloro-pyrazinium mesitylenate
• CAS No.: 1360612-56-1
• Molecular Formula: C₄H₆ClN₄*C₉H₁₁O₃S
• Molecular Weight: 344.822
• Mol file: 1360612-56-1.mol

Synonyms:1,2-diamino-3-chloro-pyrazinium mesitylenate

Chemical Property of 1,2-diamino-3-chloro-pyrazinium mesitylenate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 1,2-diamino-3-chloro-pyrazinium mesitylenate

There total 3 articles about 1,2-diamino-3-chloro-pyrazinium mesitylenate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

3-chloropyrazin-2-amine (6863-73-6) + mesitylenesulfonylhydroxylamine (36016-40-7) → 1,2-diamino-3-chloro-pyrazinium mesitylenate (1360612-56-1)

Guidance literature:

In dichloromethane; at 20 ℃; for 3h; Concentration; Temperature; Time;

Reference yield:

2-mesitylenesulphonyl chloride (773-64-8) → 1,2-diamino-3-chloro-pyrazinium mesitylenate (1360612-56-1)

Guidance literature:

Multi-step reaction with 3 steps

1: triethylamine / tetrahydrofuran / 1.25 h / 0 °C / Inert atmosphere

2: trifluoroacetic acid / 0.5 h / 0 °C / Inert atmosphere

3: dichloromethane / 0.67 h / 0 - 20 °C / Inert atmosphere

With triethylamine; trifluoroacetic acid; In tetrahydrofuran; dichloromethane;

Reference yield:

N-(tert-butoxycarbonyl)-O-(mesitylsulfonyl)hydroxylamine (36016-39-4) → 1,2-diamino-3-chloro-pyrazinium mesitylenate (1360612-56-1)

Guidance literature:

Multi-step reaction with 2 steps

1: trifluoroacetic acid / 0.5 h / 0 °C / Inert atmosphere

2: dichloromethane / 0.67 h / 0 - 20 °C / Inert atmosphere

With trifluoroacetic acid; In dichloromethane;

upstream raw materials:

3-chloropyrazin-2-amine

mesitylenesulfonylhydroxylamine

N-(tert-butoxycarbonyl)-O-(mesitylsulfonyl)hydroxylamine

2-mesitylenesulphonyl chloride

Downstream raw materials:

8-chloro-[1,2,4]triazolo[1,5-a]pyrazin-2-yl-phenyl-amine

8-chloro-[1,2,4]triazolo[1,5-a]pyrazin-2-yl-m-tolyl-amine

8-chloro-[1,2,4]triazolo[1,5-a]pyrazin-2-yl-(3,5-dimethyl-phenyl)amine

8-chloro-[1,2,4]triazolo[1,5-a]pyrazin-2-yl-(3,5-dimethoxy-phenyl)amine