di-(E)-feruloylspermidine

Base Information

• Chemical Name: di-(E)-feruloylspermidine
• CAS No.: 101330-61-4
• Molecular Formula: C₂₇H₃₅N₃O₆
• Molecular Weight: 497.591
• Mol file: 101330-61-4.mol

Synonyms:di-(E)-feruloylspermidine

Chemical Property of di-(E)-feruloylspermidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of di-(E)-feruloylspermidine

There total 3 articles about di-(E)-feruloylspermidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E)-3-(4-hydroxy-3-methoxyphenyl)acrylic acid (1135-24-6,537-98-4) → di-(E)-feruloylspermidine (101330-61-4)

Guidance literature:

Multi-step reaction with 3 steps

1: N(C₂H₅)3 / 1) CH₂Cl₂, O deg C_., 1 h., 2) room temp., 18 h

2: NH₄OH / methanol / 3 h / Ambient temperature

3: tetrahydrofuran / 18 h / Heating

With ammonium hydroxide; triethylamine; In tetrahydrofuran; methanol;

DOI:10.1016/S0040-4039(00)81595-6

Reference yield:

(E)-3-(3-Methoxy-4-methoxycarbonyloxy-phenyl)-acrylic acid piperidin-1-yl ester (86530-08-7) → di-(E)-feruloylspermidine (101330-61-4)

Guidance literature:

Multi-step reaction with 2 steps

1: NH₄OH / methanol / 3 h / Ambient temperature

2: tetrahydrofuran / 18 h / Heating

With ammonium hydroxide; In tetrahydrofuran; methanol;

DOI:10.1016/S0040-4039(00)81595-6

Reference yield:

N-(3-aminopropyl)-1,4-diaminobutane (124-20-9) + (E)-3-(4-Hydroxy-3-methoxy-phenyl)-acrylic acid piperidin-1-yl ester (86530-09-8) → di-(E)-feruloylspermidine (101330-61-4)

Guidance literature:

In tetrahydrofuran; for 18h; Heating;

DOI:10.1016/S0040-4039(00)81595-6

upstream raw materials:

N-(3-aminopropyl)-1,4-diaminobutane

(E)-3-(4-Hydroxy-3-methoxy-phenyl)-acrylic acid piperidin-1-yl ester

(E)-3-(4-hydroxy-3-methoxyphenyl)acrylic acid

(E)-3-(3-Methoxy-4-methoxycarbonyloxy-phenyl)-acrylic acid piperidin-1-yl ester

Downstream raw materials:

(E)-3-(4-hydroxy-3-methoxyphenyl)acrylic acid