Pharmakon1600-01503102

Base Information

Chemical Name:Pharmakon1600-01503102
CAS No.:37661-08-8
Molecular Formula:C21H27 N3 O7 S . Cl H
Molecular Weight:501.988
Hs Code.:
NSC Number:758228
Mol file:37661-08-8.mol

Synonyms:SR-05000001824;SPECTRUM1503102;Pharmakon1600-01503102;CCG-39301;NSC758228;SR-05000001824-3

Suppliers and Price of Pharmakon1600-01503102

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Bacampicillin hydrochloride
50mg
$ 370.00

TRC
Bacampicillin hydrochloride
25mg
$ 185.00

Sigma-Aldrich
Bacampicillin hydrochloride European Pharmacopoeia (EP) Reference Standard
$ 190.00

Sigma-Aldrich
Bacampicillin hydrochloride European Pharmacopoeia (EP) Reference Standard
b0070000
$ 190.00

ChemScene
Bacampicillin hydrochloride 99.61%
10mg
$ 90.00

ChemScene
Bacampicillin hydrochloride 99.61%
50mg
$ 260.00

American Custom Chemicals Corporation
BACAMPICILLIN HYDROCHLORIDE 95.00%
10MG
$ 280.35

Total 30 raw suppliers

Chemical Property of Pharmakon1600-01503102

Chemical Property:

Vapor Pressure:1.39E-19mmHg at 25°C
Melting Point:171-176° (dec)
Boiling Point:695.4°C at 760 mmHg
Flash Point:374.3°C
PSA：162.56000
LogP:3.12690
Solubility.:Soluble in water, freely soluble in ethanol (96 per cent), soluble in methylene chloride.
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:10
Exact Mass:501.1336491
Heavy Atom Count:33
Complexity:756

Purity/Quality:

97% ^*data from raw suppliers

Bacampicillin hydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)OC(C)OC(=O)C1C(SC2N1C(=O)C2NC(=O)C(C3=CC=CC=C3)N)(C)C.Cl
Isomeric SMILES:CCOC(=O)OC(C)OC(=O)C1C(SC2N1C(=O)C2NC(=O)[C@@H](C3=CC=CC=C3)N)(C)C.Cl
Uses Bacampicillin is a penicillin class of antibiotic. Bacampicillin is a prodrug of ampicillin (A634300) with improved oral bioavailability.
Therapeutic Function Antibacterial
Clinical Use Bacampicillin hydrochloride (Spectrobid) is the hydrochloridesalt of the 1-ethoxycarbonyloxyethyl ester of ampicillin.It is a prodrug of ampicillin with no antibacterial activity.After oral absorption, bacampicillin is hydrolyzed rapidly byesterases in the plasma to form ampicillin.Oral absorption of bacampicillin is more rapid and completethan that of ampicillin and less affected by food.Plasma levels of ampicillin from oral bacampicillin exceedthose of oral ampicillin or amoxicillin for the first 2.5 hoursbut thereafter are the same as for ampicillin and amoxicillin.49 Effective plasma levels are sustained for 12 hours,allowing twice-a-day dosing.

Technology Process of Pharmakon1600-01503102

There total 3 articles about Pharmakon1600-01503102 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%