Azinphos-methyl

Base Information

• Chemical Name: Azinphos-methyl
• CAS No.: 86-50-0
• Deprecated CAS: 54182-73-9
• Molecular Formula: C10H12 N3 O3 P S2
• Molecular Weight: 317.329
• Hs Code.: 2933990011
• European Community (EC) Number: 201-676-1
• ICSC Number: 0826
• UN Number: 2783
• UNII: 265842EWUV
• DSSTox Substance ID: DTXSID3020122
• Nikkaji Number: J4.261G
• Wikipedia: Azinphos-methyl
• Wikidata: Q418031
• NCI Thesaurus Code: C163588
• Metabolomics Workbench ID: 52987
• ChEMBL ID: CHEMBL530115
• Mol file: 86-50-0.mol

Synonyms:Azinphos Methyl;Azinphos-Methyl;Azinphosmethyl;Guthion

Chemical Property of Azinphos-methyl

Chemical Property:

• Appearance/Colour: COLOURLESS CRYSTALS
• Vapor Pressure: 2.64E-07mmHg at 25°C
• Melting Point: 73-74
• Refractive Index: 1.6115 (589.3 nm 76℃)
• Boiling Point: 421.3 °C at 760 mmHg
• PKA: -2.60±0.20(Predicted)
• Flash Point: 208.6 °C
• PSA: 133.44000
• Density: 1.51 g/cm³
• LogP: 2.65010
• Storage Temp.: 0-6°C
• Water Solubility.: 28 mg l-1(20 °C)
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 5
• Exact Mass: 317.00577060
• Heavy Atom Count: 19
• Complexity: 413
• Transport DOT Label: Poison

Purity/Quality:

Azinphos-methyl ^*data from reagent suppliers

Safty Information:

• Pictogram(s): A poison, cholinesterase inhibitor. Absorbed by skin. TLV: 0.2 mg/m³.
• Hazard Codes: T+,N
• Statements: 24-26/28-43-50/53-28
• Safety Statements: 28-36/37-45-60-61

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Pesticides -> Organophosphate Insecticides
• Canonical SMILES: COP(=S)(OC)SCN1C(=O)C2=CC=CC=C2N=N1
• Inhalation Risk: Evaporation at 20 °C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying or when dispersed, especially if powdered.
• Effects of Short Term Exposure: The substance may cause effects on the nervous system. This may result in convulsions and respiratory failure. Cholinesterase inhibition. Exposure could cause unconsciousness and death. The effects may be delayed. Medical observation is indicated.
• Effects of Long Term Exposure: Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms.
• Uses: Azinphos-methyl is used to control a wide range of both sucking and chewing insects and spider mites in a wide range of crops. Insecticide for fruit. Use may be restricted. Nonsystemic insecticide and acaricide for control of insects pests in blueberry, grape, maize, vegetable, cotton and citrus crops.

Technology Process of Azinphos-methyl

There total 4 articles about Azinphos-methyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-chloromethyl-1,2,3-benzotriazin-4(3H)-one (24310-41-6) → Azinphos-methyl (86-50-0,54182-73-9)

Guidance literature:

With acetone;

Reference yield:

1,2,3-benzotriazin-4(3H)-one (90-16-4) → Azinphos-methyl (86-50-0,54182-73-9)

Guidance literature:

Multi-step reaction with 3 steps

1: water

2: SOCl₂

3: acetone

With thionyl chloride; water; acetone;

Reference yield:

3-(hydroxymethyl)benzotriazin-4(3H)-one (24310-40-5) → Azinphos-methyl (86-50-0,54182-73-9)

Guidance literature:

Multi-step reaction with 2 steps

1: SOCl₂

2: acetone

With thionyl chloride; acetone;

upstream raw materials:

3-chloromethyl-1,2,3-benzotriazin-4(3H)-one

1,2,3-benzotriazin-4(3H)-one

3-(hydroxymethyl)benzotriazin-4(3H)-one

Refernces

• 1、 -. "Concentrates of organophosphorous insecticides". . . Retrieved 2008/06/13.