diethyl N-<4-<2-(2,4-diamino-5-deaza-6-pteridyl)ethenyl>benzoyl>-L-glutamate

Base Information

Chemical Name:diethyl N-<4-<2-(2,4-diamino-5-deaza-6-pteridyl)ethenyl>benzoyl>-L-glutamate
CAS No.:95674-67-2
Molecular Formula:C₂₅H₂₈N₆O₅
Molecular Weight:492.535
Hs Code.:

Synonyms:diethyl N-<4-<2-(2,4-diamino-5-deaza-6-pteridyl)ethenyl>benzoyl>-L-glutamate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of diethyl N-<4-<2-(2,4-diamino-5-deaza-6-pteridyl)ethenyl>benzoyl>-L-glutamate

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Technology Process of diethyl N-<4-<2-(2,4-diamino-5-deaza-6-pteridyl)ethenyl>benzoyl>-L-glutamate

There total 2 articles about diethyl N-<4-<2-(2,4-diamino-5-deaza-6-pteridyl)ethenyl>benzoyl>-L-glutamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 34.5%

: 80360-04-9
2,4-Diamino-6-(carboxaldehyde)pyrido[2,3-d]pyrimidine

: 70583-34-5
[4-((S)-1,3-Bis-ethoxycarbonyl-propylcarbamoyl)-benzyl]-triphenyl-phosphonium; bromide

: 95674-67-2
diethyl N-<4-<2-(2,4-diamino-5-deaza-6-pteridyl)ethenyl>benzoyl>-L-glutamate

Guidance literature:: With 1-methyl-pyrrolidin-2-one; sodium hydride; for 504h; Ambient temperature;
DOI:10.1021/jm00145a012

Reference yield:

: 1118-89-4
diethyl-L-glutamate hydrochloride

: 95674-66-1
2,4-diamino-6-(4-carboxystyryl)-5-deazapteridine

: 95674-67-2
diethyl N-<4-<2-(2,4-diamino-5-deaza-6-pteridyl)ethenyl>benzoyl>-L-glutamate

Guidance literature:: With 4-methyl-morpholine; 1-methyl-pyrrolidin-2-one; chlorophosphoric acid diphenyl ester; Yield given. Multistep reaction; 1.) 5 deg C, 1 h, 2.) RT, overnight;
DOI:10.1021/jm00145a012

Reference yield: 31.0%

: 95674-67-2
diethyl N-<4-<2-(2,4-diamino-5-deaza-6-pteridyl)ethenyl>benzoyl>-L-glutamate

: 95693-79-1
diethyl N-<4-<2-(2,4-diamino-5-deaza-5,6,7,8-tetrahydro-6-pteridyl)ethyl>benzoyl>-L-glutamate

Guidance literature:: With hydrogen; trifluoroacetic acid; palladium on activated charcoal; for 72h; under 2844.3 Torr;
DOI:10.1021/jm00145a012