4-[4-(2-methyl-5-chlorophenyl)-1-piperazinyl]phenyl-1-3-(2H,4H)-1,2,4-triazolone

Base Information

Chemical Name:4-[4-(2-methyl-5-chlorophenyl)-1-piperazinyl]phenyl-1-3-(2H,4H)-1,2,4-triazolone
CAS No.:359826-09-8
Molecular Formula:C₁₉H₂₀ClN₅O
Molecular Weight:369.854
Hs Code.:

Synonyms:4-[4-(2-methyl-5-chlorophenyl)-1-piperazinyl]phenyl-1-3-(2H,4H)-1,2,4-triazolone

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-[4-(2-methyl-5-chlorophenyl)-1-piperazinyl]phenyl-1-3-(2H,4H)-1,2,4-triazolone

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Technology Process of 4-[4-(2-methyl-5-chlorophenyl)-1-piperazinyl]phenyl-1-3-(2H,4H)-1,2,4-triazolone

There total 1 articles about 4-[4-(2-methyl-5-chlorophenyl)-1-piperazinyl]phenyl-1-3-(2H,4H)-1,2,4-triazolone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: C₁₈H₂₂ClN₅O

: 3473-63-0
formamidine acetic acid

: 359826-09-8
4-[4-(2-methyl-5-chlorophenyl)-1-piperazinyl]phenyl-1-3-(2H,4H)-1,2,4-triazolone

Guidance literature:: In DMF (N,N-dimethyl-formamide); at 120 ℃; for 3 - 5h;

Reference yield: 71.0%

: 359826-09-8
4-[4-(2-methyl-5-chlorophenyl)-1-piperazinyl]phenyl-1-3-(2H,4H)-1,2,4-triazolone

: 126917-43-9,135133-19-6,138457-39-3
2-chloro-1-(2,4-difluorophenyl)propan-1-one

: 359826-10-1
2-{4-[4-[4-(2-methyl-5-chlorophenyl)piperazinyl]phenyl]-(2H,4H)-1,2,4-triazol-3-one-2-yl}-2(R/S)-methyl-2,4-difluoroacetophenone

Guidance literature:: 4-[4-(2-methyl-5-chlorophenyl)-1-piperazinyl]phenyl-1-3-(2H,4H)-1,2,4-triazolone; With sodium hydride; In dimethyl sulfoxide; at 25 - 30 ℃; for 1h;

2-chloro-1-(2,4-difluorophenyl)propan-1-one; In dimethyl sulfoxide; at 15 - 60 ℃; for 5 - 6h;