Flualprazolam

Base Information

• Chemical Name: Flualprazolam
• CAS No.: 28910-91-0
• Molecular Formula: C₁₇H₁₂ClFN₄
• Molecular Weight: 326.76
• European Community (EC) Number: 878-264-9
• UNII: FWF5L8D2BE
• DSSTox Substance ID: DTXSID801132654
• Wikipedia: Flualprazolam
• Wikidata: Q62018618

Synonyms:flualprazolam

 This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of Flualprazolam

Chemical Property:

• Boiling Point: 509.8±60.0 °C(Predicted)
• Density: 1.43±0.1 g/cm3(Predicted)
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 326.0734523
• Heavy Atom Count: 23
• Complexity: 474

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=NN=C2N1C3=C(C=C(C=C3)Cl)C(=NC2)C4=CC=CC=C4F
• Description: Flualprazolam (Item No. 24481) is an analytical reference material categorized as a benzodiazepine. This product is intended for research and forensic applications.Flualprazolam is structurally related to the triazolo-benzodiazepine, alprazolam. As a class of drugs, benzodiazepines produce central nervous system (CNS) depression and are commonly used to treat, panic disorders, anxiety, and insomnia. The United States Food and Drug Administration has not approved flualprazolam for therapeutic use.
• Uses: Illicit Uses: Flualprazolam is generally abused for its sedative/hypnotic effects. Reports from online drug user forums describe it to be similar to clonazepam and alprazolam.User Population: Flualprazolam is used as a recreational substance in the United States. It is generally abused by young adults, especially males.

Technology Process of Flualprazolam

There total 5 articles about Flualprazolam which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

acetic acid hydrazide (1068-57-1) + 7-chloro-5-(2-fluorophenyl)-2-(N-nitrosomethylamino)-3H-1,4-benzodiazepine (59467-62-8) → flualprazolam (28910-91-0)

Guidance literature:

With toluene-4-sulfonic acid; In N,N-dimethyl-formamide; at 120 ℃; for 1h;

DOI:10.3390/11080583

Reference yield: 81.2%

acetic acid hydrazide (1068-57-1) + 7-chloro-5-(2-fluorophenyl)-1,3-dihydro-1,4-benzodiazepin-2(2H)-one (2886-65-9) → flualprazolam (28910-91-0)

Guidance literature:

In butan-1-ol; at 125 ℃; for 8h; Temperature; Solvent;

Reference yield:

7-chloro-1,3-dihydro-5-(2-fluorophenyl)-2H-1,4-benzodiazepine-2-thione (1645-32-5) → flualprazolam (28910-91-0)

Guidance literature:

In dichloromethane; water; butan-1-ol;

upstream raw materials:

acetic acid hydrazide

7-chloro-5-(2-fluorophenyl)-2-(N-nitrosomethylamino)-3H-1,4-benzodiazepine

7-chloro-1,3-dihydro-5-(2-fluorophenyl)-2H-1,4-benzodiazepine-2-thione

7-chloro-5-(2-fluorophenyl)-1,3-dihydro-1,4-benzodiazepin-2(2H)-one