2,3,5-TRICHLOROPHENOL ACETATE

Base Information

• Chemical Name: 2,3,5-TRICHLOROPHENOL ACETATE
• CAS No.: 61925-88-0
• Molecular Formula: C8H5Cl3O2
• Molecular Weight: 239.485
• Mol file: 61925-88-0.mol

Synonyms:Acetic acid,2,3,5-trichlorophenyl ester;2,3,5-trichlorophenol acetate;Phenol,2,3,5-trichloro,acetate;2,3,5-Trichlorophenyl acetate;

Chemical Property of 2,3,5-TRICHLOROPHENOL ACETATE

Chemical Property:

• Vapor Pressure: 0.000627mmHg at 25°C
• Boiling Point: 309.7°C at 760 mmHg
• Flash Point: 133.9°C
• PSA: 26.30000
• Density: 1.469g/cm³
• LogP: 3.57210

Purity/Quality:

99% ^*data from raw suppliers

2,3,5-TRICHLOROPHENOL ACETATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,3,5-TRICHLOROPHENOL ACETATE

There total 7 articles about 2,3,5-TRICHLOROPHENOL ACETATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

2,3,5-trichlorophenol (933-78-8) + acetic acid (64-19-7,77671-22-8) → 2,3,5-trichlorophenyl acetate (61925-88-0)

Guidance literature:

With pyridine; Heating;

Reference yield:

2,3,5-trichlorophenol (933-78-8) + 4-nitrophenol acetate (830-03-5) → 4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + 2,3,5-trichlorophenyl acetate (61925-88-0)

Guidance literature:

In water; acetonitrile; at 25 ℃; Rate constant; Mechanism; pH 7.00;

DOI:10.1021/ja00255a021

Reference yield:

acetic anhydride (108-24-7) + potassium salt of 2,3,5-trichlorophenol (58200-72-9) → potassium acetate (127-08-2) + 2,3,5-trichlorophenyl acetate (61925-88-0)

Guidance literature:

With 18-crown-6 ether; In chlorobenzene; at 25 ℃; Rate constant; Equilibrium constant;

upstream raw materials:

4-chloro-2-nitrophenyl acetate

2,3,5-trichlorophenoxide ion

2,3,5-trichlorophenol

acetic anhydride

Downstream raw materials:

2,3,5-trichlorophenol

acetic acid

N-butylacetamide

acetic anhydride

Refernces

• 1、 Maude, Antony B.,Williams, Andrew. "Effective charge development in the transfer of the acetyl group between nucleophiles in acetonitrile solution: Acetolysis and butylaminolysis of substituted phenyl esters". . p. 179 - 183. Retrieved 2007/10/03.
• 2、 Stefanidis, Dimitrios,Cho, Sayeon,Dhe-Paganon, Sirano,Jencks, William P.. "Structure-reactivity correlations for reactions of substituted phenolate anions with acetate and formate esters". . p. 1650 - 1656. Retrieved 2007/10/02.