10-(3-(Dimethylamino)propyl)acridin-9(10H)-one

Base Information

Chemical Name:10-(3-(Dimethylamino)propyl)acridin-9(10H)-one
CAS No.:2307-88-2
Molecular Formula:C₁₈H₂₀N₂O
Molecular Weight:280.37
Hs Code.:2933990090
UNII:Q0K6203U6L
DSSTox Substance ID:DTXSID00177640
Wikidata:Q27286854
Mol file:2307-88-2.mol

Synonyms:10-(3-(Dimethylamino)propyl)acridin-9(10H)-one;2307-88-2;10-[3-(dimethylamino)propyl]acridin-9-one;9-Acridanone, 10-(3-(dimethylamino)propyl)-;Q0K6203U6L;UNII-Q0K6203U6L;10-[3-(Dimethyl-amino)propyl]acridin-9(10H)-one Hydrochloride;10-(3-(Dimethylamino)propyl)-9(10H)-acridinone;SCHEMBL10702688;DTXSID00177640;Q27286854;IMIPRAMINE HYDROCHLORIDE IMPURITY C [EP IMPURITY];9(10H)-ACRIDINONE, 10-(3-(DIMETHYLAMINO)PROPYL)-

Suppliers and Price of 10-(3-(Dimethylamino)propyl)acridin-9(10H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 7 raw suppliers

Chemical Property of 10-(3-(Dimethylamino)propyl)acridin-9(10H)-one

Chemical Property:

Vapor Pressure:1.59E-07mmHg at 25°C
Boiling Point:427.8°Cat760mmHg
Flash Point:182.7°C
PSA：25.24000
Density:1.13g/cm³
LogP:3.10640
XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:280.157563266
Heavy Atom Count:21
Complexity:342

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)CCCN1C2=CC=CC=C2C(=O)C3=CC=CC=C31

Technology Process of 10-(3-(Dimethylamino)propyl)acridin-9(10H)-one

There total 3 articles about 10-(3-(Dimethylamino)propyl)acridin-9(10H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 124-40-3
dimethyl amine

: 427883-75-8
10-(3-bromopropyl) acridin-9(10H)-one

: 2307-88-2
10-(3′-(N-dimethylamino)propyl)acridone

Guidance literature:: In acetonitrile; at 20 ℃; for 24h;
DOI:10.1177/1747519820902674

Reference yield:

: 578-95-0,790240-54-9
10H-acridin-9-one

: 2307-88-2
10-(3′-(N-dimethylamino)propyl)acridone

Guidance literature:: Multi-step reaction with 2 steps

1: 20 percent / NaH / dimethylformamide / 80 °C

2: ethanol / 24 h / 20 °C

With sodium hydride; In ethanol; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(97)00137-8

Reference yield:

: 109-54-6
3-(Dimethylamino)propyl chloride

: 578-95-0,790240-54-9
10H-acridin-9-one

: 2307-88-2
10-(3′-(N-dimethylamino)propyl)acridone

Guidance literature:: With potassium hydroxide; potassium carbonate; 18-crown-6 ether; Yield given. Multistep reaction; toluene 1.) room temp., 2 h, 2.) reflux, 18 h;
DOI:10.1055/s-1984-30719