1,4,7,10-tetraaza-1-N-(1-carbomethoxy-3-(4-nitrophenyl)propyl)cyclododecane

Base Information

• Chemical Name: 1,4,7,10-tetraaza-1-N-(1-carbomethoxy-3-(4-nitrophenyl)propyl)cyclododecane
• CAS No.: 130707-81-2
• Molecular Formula: C₁₉H₃₁N₅O₄
• Molecular Weight: 393.486
• Mol file: 130707-81-2.mol

Synonyms:1,4,7,10-tetraaza-1-N-(1-carbomethoxy-3-(4-nitrophenyl)propyl)cyclododecane

Chemical Property of 1,4,7,10-tetraaza-1-N-(1-carbomethoxy-3-(4-nitrophenyl)propyl)cyclododecane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,4,7,10-tetraaza-1-N-(1-carbomethoxy-3-(4-nitrophenyl)propyl)cyclododecane

There total 3 articles about 1,4,7,10-tetraaza-1-N-(1-carbomethoxy-3-(4-nitrophenyl)propyl)cyclododecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

methanolic chloroform + 1,4,7,10-tetraazacyclododecan (294-90-6) + d,l-2-bromo-4-(4-nitrophenyl)butanoic acid methyl ester (130707-80-1) → 1,4,7,10-tetraaza-1-N-(1-carbomethoxy-3-(4-nitrophenyl)propyl)cyclododecane (130707-81-2)

Guidance literature:

In chloroform; 1-penten;

Reference yield: 87.0%

1,4,7,10-tetraazacyclododecan (294-90-6) + d,l-2-bromo-4-(4-nitrophenyl)butanoic acid methyl ester (130707-80-1) → 1,4,7,10-tetraaza-1-N-(1-carbomethoxy-3-(4-nitrophenyl)propyl)cyclododecane (130707-81-2)

Guidance literature:

In chloroform; at 20 ℃; for 56h;

DOI:10.1016/S0968-0896(99)00171-6

Reference yield:

methanol (67-56-1) + 4-(4-nitrophenyl)butanoic acid (5600-62-4) + 1,4,7,10-tetraazacyclododecan (294-90-6) → 1,4,7,10-tetraaza-1-N-(1-carbomethoxy-3-(4-nitrophenyl)propyl)cyclododecane (130707-81-2)

Guidance literature:

Yield given. Multistep reaction;

DOI:10.1021/jo00067a018

upstream raw materials:

methanol

4-(4-nitrophenyl)butanoic acid

1,4,7,10-tetraazacyclododecan

d,l-2-bromo-4-(4-nitrophenyl)butanoic acid methyl ester

Downstream raw materials:

1,4,7,10-tetraaza-N-(1-carbomethoxy-3-(4-nitrophenyl)propyl)-N',N'',N'''-tris(acetic acid, ethyl ester)cyclododecane

C₄₀H₆₁N₅O₁₆

α-[2-(4-nitrophenyl)ethyl]-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid, 1,4,7,10-tetramethyl ester

α-[2-(4-aminophenyl)ethyl]-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid