2-Cyano-2-methylpyrrolidine

Base Information

Chemical Name:2-Cyano-2-methylpyrrolidine
CAS No.:42457-13-6
Molecular Formula:C₆H₁₀N₂
Molecular Weight:110.159
Hs Code.:
DSSTox Substance ID:DTXSID501296221

Synonyms:42457-13-6;2-Cyano-2-methylpyrrolidine;SCHEMBL14235245;DVHZDPNOAOREHX-UHFFFAOYSA-N;2-Methyl-2-pyrrolidinecarbonitrile;2-methylpyrrolidine-2-carbonitrile;DTXSID501296221;AT36485;2-METHYLPYRROLIDINE-2-CARBONITRILE (CONTAINING 13% 5-METHYL-3,4-DIHYDRO-2H-PYRROLE)

Suppliers and Price of 2-Cyano-2-methylpyrrolidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 2-Cyano-2-methylpyrrolidine

Chemical Property:

XLogP3:0.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:110.084398327
Heavy Atom Count:8
Complexity:133

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1(CCCN1)C#N

Technology Process of 2-Cyano-2-methylpyrrolidine

There total 1 articles about 2-Cyano-2-methylpyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5891-21-4
5-chloro-2-pentanone

: 773837-37-9
sodium cyanide

: 872-32-2
2-methyl-1H-pyrroline

: 42457-13-6
2-cyano-2-methylpyrrolidine

Guidance literature:: 5-chloro-2-pentanone; With ammonium acetate; In water; tert-butyl alcohol; at 50 ℃; for 2.5h;

sodium cyanide; In water; tert-butyl alcohol; for 2.5h; Solvent; Time; Temperature;

Reference yield:

: 42457-13-6
2-cyano-2-methylpyrrolidine

: 42856-71-3
(S)-2-methylpyrrolidine-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: sulfuric acid; water / ethyl acetate / 6 h / 20 - 40 °C / Cooling with ice

1.2: Reflux

2.1: sodium hydroxide; peptidase R / water / 161 h / 40 °C / pH 6.8 / Enzymatic reaction

With peptidase R; sulfuric acid; water; sodium hydroxide; In water; ethyl acetate;

Reference yield:

: 42457-13-6
2-cyano-2-methylpyrrolidine

: 132235-42-8
(2R)-2-methyl-2-pyrrolidinecarboxamide

: 42856-71-3
(S)-2-methylpyrrolidine-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: sulfuric acid; water / ethyl acetate / 6 h / 20 - 40 °C / Cooling with ice

1.2: Reflux

2.1: sodium hydroxide; peptidase R; water / 162 h / 40 °C / pH 7 / Enzymatic reaction

With peptidase R; sulfuric acid; water; sodium hydroxide; In ethyl acetate;