N-[(2-azidophenyl)(butylcarbamoyl)methyl]-N-butylethanamide

Base Information

• Chemical Name: N-[(2-azidophenyl)(butylcarbamoyl)methyl]-N-butylethanamide
• CAS No.: 1220273-12-0
• Molecular Formula: C₁₈H₂₇N₅O₂
• Molecular Weight: 345.445
• Mol file: 1220273-12-0.mol

Synonyms:N-[(2-azidophenyl)(butylcarbamoyl)methyl]-N-butylethanamide

Chemical Property of N-[(2-azidophenyl)(butylcarbamoyl)methyl]-N-butylethanamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-[(2-azidophenyl)(butylcarbamoyl)methyl]-N-butylethanamide

There total 1 articles about N-[(2-azidophenyl)(butylcarbamoyl)methyl]-N-butylethanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

n-butyl isonitrile (2769-64-4) + 2-azidobenzaldehyde (16714-25-3) + acetic acid (64-19-7,77671-22-8) + N-butylamine (109-73-9,85404-21-3) → N-[(2-azidophenyl)(butylcarbamoyl)methyl]-N-butylethanamide (1220273-12-0)

Guidance literature:

In methanol; at 20 ℃; for 24h;

DOI:10.1002/ejoc.200901287

Reference yield: 67.0%

N-[(2-azidophenyl)(butylcarbamoyl)methyl]-N-butylethanamide (1220273-12-0) + p-chlorphenylisocyanate (104-12-1) → N-butyl-2-[N-(4-chlorophenyl)benzamido]-3-propyl-3,4-dihydroquinazoline-4-carboxamide (1220273-56-2)

Guidance literature:

N-[(2-azidophenyl)(butylcarbamoyl)methyl]-N-butylethanamide; With triphenylphosphine; In toluene; at 20 ℃;

p-chlorphenylisocyanate; In toluene; at 20 ℃;

In toluene; for 8h; Reflux;

DOI:10.1002/ejoc.200901287

upstream raw materials:

n-butyl isonitrile

2-azidobenzaldehyde

acetic acid

N-butylamine

Downstream raw materials:

N-butyl-2-[N-(4-chlorophenyl)benzamido]-3-propyl-3,4-dihydroquinazoline-4-carboxamide