(S)-tert-butyl 2-{[(2-benzoylphenyl)amino]carbonyl}pyrrolidine-1-carboxylate

Base Information

• Chemical Name: (S)-tert-butyl 2-{[(2-benzoylphenyl)amino]carbonyl}pyrrolidine-1-carboxylate
• CAS No.: 1093987-00-8
• Molecular Formula: C₂₃H₂₆N₂O₄
• Molecular Weight: 394.47
• Mol file: 1093987-00-8.mol

Synonyms:(S)-tert-butyl 2-{[(2-benzoylphenyl)amino]carbonyl}pyrrolidine-1-carboxylate

Chemical Property of (S)-tert-butyl 2-{[(2-benzoylphenyl)amino]carbonyl}pyrrolidine-1-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (S)-tert-butyl 2-{[(2-benzoylphenyl)amino]carbonyl}pyrrolidine-1-carboxylate

There total 1 articles about (S)-tert-butyl 2-{[(2-benzoylphenyl)amino]carbonyl}pyrrolidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1-(tert-butoxycarbonyl)-L-proline (15761-39-4,59433-50-0) + (2-aminophenyl)(phenyl)methanone (2835-77-0) → (S)-tert-butyl 2-{[(2-benzoylphenyl)amino]carbonyl}pyrrolidine-1-carboxylate (1093987-00-8)

Guidance literature:

With triethylamine; isobutyl chloroformate; In tetrahydrofuran; at 0 ℃;

DOI:10.1016/j.tetlet.2008.09.168

Reference yield: 100.0%

(S)-tert-butyl 2-{[(2-benzoylphenyl)amino]carbonyl}pyrrolidine-1-carboxylate (1093987-00-8) → L-proline-2-aminobenzophenone amide hydrochloride (1609121-29-0)

Guidance literature:

With hydrogenchloride; In acetonitrile; at 20 - 25 ℃; Large scale;

Reference yield: 100.0%

(S)-tert-butyl 2-{[(2-benzoylphenyl)amino]carbonyl}pyrrolidine-1-carboxylate (1093987-00-8) → N-(2-benzoylphenyl)-L-prolinamide (117186-74-0,1609156-63-9)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃;

DOI:10.1016/j.tetlet.2008.09.168

upstream raw materials:

1-(tert-butoxycarbonyl)-L-proline

(2-aminophenyl)(phenyl)methanone

Downstream raw materials:

N-(2-benzoylphenyl)-L-prolinamide

(S)-tert-butyl 2-{[(2-benzoylphenyl)(methyl)amino]carbonyl}pyrrolidine-1-carboxylate

L-proline-2-aminobenzophenone amide hydrochloride

(S)-2-N-[N'-(2-fluorobenzyl)prolyl]aminobenzophenone hydrochloride