Clofenoxyde

Base Information

• Chemical Name: Clofenoxyde
• CAS No.: 3030-53-3
• Molecular Formula: C16H12 Cl2 O3
• Molecular Weight: 323.175
• Hs Code.: 2914700090
• Mol file: 3030-53-3.mol

Synonyms:Acetophenone,4',4'''-oxybis[2-chloro- (7CI,8CI); 2087 CB; 4,4'-Bis(chloroacetyl)diphenylether; 4,4'-Oxybis[2-chloroacetophenone]; Bis(4-chloroacetophenyl) ether;Bis(4-chloroacetyl)diphenyl ether; Bis(4-chloroacetylphenyl) ether;Clofenoxide; Clofenoxyde; Stamycil

Chemical Property of Clofenoxyde

Chemical Property:

• Vapor Pressure: 2.04E-09mmHg at 25°C
• Melting Point: 102 °C
• Boiling Point: 481.2°C at 760 mmHg
• Flash Point: 192°C
• PSA: 43.37000
• Density: 1.314g/cm³
• LogP: 4.32190

Purity/Quality:

97%+ ^*data from raw suppliers

CLOFENOXYDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Clofenoxyde

There total 3 articles about Clofenoxyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

diphenylether (101-84-8) + chloroacetyl chloride (79-04-9) → 4,4'-bis(chloroacetyl)diphenyl ether (3030-53-3)

Guidance literature:

With carbon disulfide; aluminum (III) chloride; at 0 ℃; for 6h;

DOI:10.1039/c6ra28756e

Reference yield:

Chloroiodomethane (593-71-5) + dimethyl 4,4'-oxydibenzoate (14387-30-5) → 4,4'-bis(chloroacetyl)diphenyl ether (3030-53-3)

Guidance literature:

Chloroiodomethane; dimethyl 4,4'-oxydibenzoate; With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃; for 0.25h;

With acetic acid; In tetrahydrofuran; at -78 ℃; for 0.166667h;

Reference yield:

→ 4,4'-bis(chloroacetyl)diphenyl ether (3030-53-3)

Guidance literature:

2-Chlor-ethanoyl u. Diphenyloxid;

upstream raw materials:

diphenylether

chloroacetyl chloride

Chloroiodomethane

dimethyl 4,4'-oxydibenzoate

Downstream raw materials:

bis-(4-acetoxyacetyl-phenyl)-ether

bis-(4-glycyl-phenyl)-ether ; dihydrochloride

C₃₆H₄₆N₄O₉

C₃₆H₄₄N₆O₅

Refernces

• 1、 Ceylan, Yusuf,Usta, Ayhan,Usta, Keziban,Durmaz, Fatih,Co?kun, Ahmet. "Determination of free radical on polycrystal of 4,4′- bis(chloroacetyl)diphenylether: An ESR study". . p. 69 - 72. Retrieved 2013.
• 2、 -. "DIARYL ETHERS". Page/Page column 25. . Retrieved 2010/11/05.