α-benzoylaminocinnamic acid amide

Base Information

• Chemical Name: α-benzoylaminocinnamic acid amide
• CAS No.: 70985-09-0
• Molecular Formula: C₁₆H₁₄N₂O₂
• Molecular Weight: 266.299
• Mol file: 70985-09-0.mol

Synonyms:α-benzoylaminocinnamic acid amide

Chemical Property of α-benzoylaminocinnamic acid amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of α-benzoylaminocinnamic acid amide

There total 10 articles about α-benzoylaminocinnamic acid amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

(4Z)-4-benzylidene-2-phenyl-1,3-oxazol-5(4H)-one (17606-70-1,5839-91-8) → (Z)-2-benzoylamino-3-phenylprop-2-enamide (70985-09-0)

Guidance literature:

With 1,1,1,3,3,3-hexamethyl-disilazane; In ethyl acetate; at 25 ℃; for 24h;

DOI:10.1134/S1070428007060127

Reference yield:

4-benzylidene-2-phenyloxazole-5(4H)-one (842-74-0,5839-91-8) → α-benzoylaminocinnamic acid amide (70985-09-0)

Guidance literature:

With ammonia; In methanol; chloroform; at 0 ℃;

DOI:10.1039/c4ob00309h

Reference yield:

benzaldehyde (100-52-7) → α-benzoylaminocinnamic acid amide (70985-09-0)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic anhydride / 100 °C

2: ammonia / chloroform; methanol / 0 °C

With ammonia; acetic anhydride; In methanol; chloroform;

DOI:10.1039/c4ob00309h

upstream raw materials:

(4Z)-4-benzylidene-2-phenyl-1,3-oxazol-5(4H)-one

(E)-2-phenyl-4-benzylidene-5(4H)-oxazolone

hippuramide

benzaldehyde

Downstream raw materials:

4-benzylidene-2-phenylimidazol-5(4H)-one

N-(1-amino-1-oxo-3-phenylpropan-2-yl)benzamide

(Z)-N-(3-amino-1-bromo-3-oxo-1-phenylprop-1-en-2-yl)benzamide

2,5-diphenyloxazole-4-carboxamide