(Z)-N-(3-amino-1-bromo-3-oxo-1-phenylprop-1-en-2-yl)benzamide

Base Information

• Chemical Name: (Z)-N-(3-amino-1-bromo-3-oxo-1-phenylprop-1-en-2-yl)benzamide
• CAS No.: 1643501-30-7
• Molecular Formula: C₁₆H₁₃BrN₂O₂
• Molecular Weight: 345.195
• Mol file: 1643501-30-7.mol

Synonyms:(Z)-N-(3-amino-1-bromo-3-oxo-1-phenylprop-1-en-2-yl)benzamide

Chemical Property of (Z)-N-(3-amino-1-bromo-3-oxo-1-phenylprop-1-en-2-yl)benzamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (Z)-N-(3-amino-1-bromo-3-oxo-1-phenylprop-1-en-2-yl)benzamide

There total 3 articles about (Z)-N-(3-amino-1-bromo-3-oxo-1-phenylprop-1-en-2-yl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

α-benzoylaminocinnamic acid amide (70985-09-0) → (Z)-N-(3-amino-1-bromo-3-oxo-1-phenylprop-1-en-2-yl)benzamide (1643501-30-7)

Guidance literature:

With bromine; calcium carbonate; In chloroform; at 0 - 20 ℃;

DOI:10.1039/c4ob00309h

Reference yield:

4-benzylidene-2-phenyloxazole-5(4H)-one (842-74-0,5839-91-8) → (Z)-N-(3-amino-1-bromo-3-oxo-1-phenylprop-1-en-2-yl)benzamide (1643501-30-7)

Guidance literature:

Multi-step reaction with 2 steps

1: ammonia / chloroform; methanol / 0 °C

2: bromine; calcium carbonate / chloroform / 0 - 20 °C

With ammonia; bromine; calcium carbonate; In methanol; chloroform;

DOI:10.1039/c4ob00309h

Reference yield:

benzaldehyde (100-52-7) → (Z)-N-(3-amino-1-bromo-3-oxo-1-phenylprop-1-en-2-yl)benzamide (1643501-30-7)

Guidance literature:

Multi-step reaction with 3 steps

1: acetic anhydride / 100 °C

2: ammonia / chloroform; methanol / 0 °C

3: bromine; calcium carbonate / chloroform / 0 - 20 °C

With ammonia; bromine; acetic anhydride; calcium carbonate; In methanol; chloroform;

DOI:10.1039/c4ob00309h

upstream raw materials:

α-benzoylaminocinnamic acid amide

4-benzylidene-2-phenyloxazole-5(4H)-one

benzaldehyde

Downstream raw materials:

2,5-diphenyloxazole-4-carboxamide