ethyl 4-[4-(isochroman-1-ylcarbonylamino)benzoylamino]benzoate

Base Information

• Chemical Name: ethyl 4-[4-(isochroman-1-ylcarbonylamino)benzoylamino]benzoate
• CAS No.: 1089958-80-4
• Molecular Formula: C₂₆H₂₄N₂O₅
• Molecular Weight: 444.487
• Mol file: 1089958-80-4.mol

Synonyms:ethyl 4-[4-(isochroman-1-ylcarbonylamino)benzoylamino]benzoate

Chemical Property of ethyl 4-[4-(isochroman-1-ylcarbonylamino)benzoylamino]benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of ethyl 4-[4-(isochroman-1-ylcarbonylamino)benzoylamino]benzoate

There total 4 articles about ethyl 4-[4-(isochroman-1-ylcarbonylamino)benzoylamino]benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

C17H14ClNO3 (1408397-42-1) + p-aminoethylbenzoate (94-09-7) → ethyl 4-[4-(isochroman-1-ylcarbonylamino)benzoylamino]benzoate (1089958-80-4)

Guidance literature:

With pyridine; In 1,4-dioxane; at 70 - 75 ℃;

DOI:10.1134/S1070428012070147

Reference yield:

3,4-dihydro-1H-2-benzopyran-1-carboxylic acid (13328-85-3) → ethyl 4-[4-(isochroman-1-ylcarbonylamino)benzoylamino]benzoate (1089958-80-4)

Guidance literature:

Multi-step reaction with 4 steps

1: thionyl chloride

2: pyridine / 1,4-dioxane / 70 °C

3: thionyl chloride / toluene / 10 h / 80 - 85 °C

4: pyridine / 1,4-dioxane / 70 - 75 °C

With pyridine; thionyl chloride; In 1,4-dioxane; toluene;

DOI:10.1134/S1070428012070147

Reference yield:

4-(isochroman-1-ylcarbonylamino)benzoic acid (1089959-17-0) → ethyl 4-[4-(isochroman-1-ylcarbonylamino)benzoylamino]benzoate (1089958-80-4)

Guidance literature:

Multi-step reaction with 2 steps

1: thionyl chloride / toluene / 10 h / 80 - 85 °C

2: pyridine / 1,4-dioxane / 70 - 75 °C

With pyridine; thionyl chloride; In 1,4-dioxane; toluene;

DOI:10.1134/S1070428012070147

upstream raw materials:

C₁₇H₁₄ClNO₃

p-aminoethylbenzoate

3,4-dihydro-1H-2-benzopyran-1-carboxylic acid

Isochroman-1-carbonsaeurechlorid