Technology Process of (1S,2S,5R)-2-isopropyl-5-methylcyclohexyl 4-(octadecylsulfonyl)benzoate
There total 5 articles about (1S,2S,5R)-2-isopropyl-5-methylcyclohexyl 4-(octadecylsulfonyl)benzoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
triphenylphosphine; diethylazodicarboxylate;
In
tetrahydrofuran;
at 0 - 20 ℃;
for 3h;
Inert atmosphere;
DOI:10.1055/s-0031-1290406
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0.25 h / 20 °C / Inert atmosphere
2.1: lithium hydroxide monohydrate; water / tetrahydrofuran / Inert atmosphere
2.2: pH < 2 / Inert atmosphere
3.1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 3 h / 0 - 20 °C / Inert atmosphere
With
lithium hydroxide monohydrate; water; 3-chloro-benzenecarboperoxoic acid; triphenylphosphine; diethylazodicarboxylate;
In
tetrahydrofuran; dichloromethane;
3.1: Mitsunobu reaction;
DOI:10.1055/s-0031-1290406
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: caesium carbonate / dimethyl sulfoxide / 0.08 h / 20 °C / Inert atmosphere; Sonication
2.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0.25 h / 20 °C / Inert atmosphere
3.1: lithium hydroxide monohydrate; water / tetrahydrofuran / Inert atmosphere
3.2: pH < 2 / Inert atmosphere
4.1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 3 h / 0 - 20 °C / Inert atmosphere
With
lithium hydroxide monohydrate; water; caesium carbonate; 3-chloro-benzenecarboperoxoic acid; triphenylphosphine; diethylazodicarboxylate;
In
tetrahydrofuran; dichloromethane; dimethyl sulfoxide;
4.1: Mitsunobu reaction;
DOI:10.1055/s-0031-1290406
