Ethyl 2-hydroxy-5-nitrobenzeneacetate

Base Information

Chemical Name:Ethyl 2-hydroxy-5-nitrobenzeneacetate
CAS No.:116435-83-7
Molecular Formula:C₁₀H₁₁NO₅
Molecular Weight:225.201
Hs Code.:
DSSTox Substance ID:DTXSID901288692

Synonyms:116435-83-7;SCHEMBL2189271;DTXSID901288692;Ethyl 2-hydroxy-5-nitrophenylacetate;Ethyl 2-hydroxy-5-nitrobenzeneacetate;ethyl 2-(2-hydroxy-5-nitrophenyl)acetate

Suppliers and Price of Ethyl 2-hydroxy-5-nitrobenzeneacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 0 raw suppliers

Chemical Property of Ethyl 2-hydroxy-5-nitrobenzeneacetate

Chemical Property:

XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:225.06372245
Heavy Atom Count:16
Complexity:262

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)CC1=C(C=CC(=C1)[N+](=O)[O-])O

Technology Process of Ethyl 2-hydroxy-5-nitrobenzeneacetate

There total 2 articles about Ethyl 2-hydroxy-5-nitrobenzeneacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 64-17-5
ethanol

: 51794-07-1
2-hydroxy-5-nitrophenylacetic acid

: 116435-83-7
(2-hydroxy-5-nitro-phenyl)-acetic acid ethyl ester

Guidance literature:: With thionyl chloride; for 6h; Heating;
DOI:10.1021/jm00032a020

Reference yield:

: 614-75-5
2-Hydroxyphenylacetic acid

: 116435-83-7
(2-hydroxy-5-nitro-phenyl)-acetic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 43 percent / aq. HNO₃ / 2 h / 5 - 25 °C

2: 85 percent / SOCl₂ / 6 h / Heating

With thionyl chloride; nitric acid;
DOI:10.1021/jm00032a020