3-(4-trimethylsilylphenyl)cyclobutanecarboxaldehyde

Base Information

• Chemical Name: 3-(4-trimethylsilylphenyl)cyclobutanecarboxaldehyde
• CAS No.: 115169-60-3
• Molecular Formula: C₁₄H₂₀OSi
• Molecular Weight: 232.398
• Mol file: 115169-60-3.mol

Synonyms:3-(4-trimethylsilylphenyl)cyclobutanecarboxaldehyde

Chemical Property of 3-(4-trimethylsilylphenyl)cyclobutanecarboxaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 3-(4-trimethylsilylphenyl)cyclobutanecarboxaldehyde

There total 1 articles about 3-(4-trimethylsilylphenyl)cyclobutanecarboxaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

oxalyl dichloride (79-37-8) + 3-(4-trimethylsilylphenyl)cyclobutylmethanol (115169-59-0) + dimethyl sulfoxide (67-68-5,8070-53-9) → 3-(4-trimethylsilylphenyl)cyclobutanecarboxaldehyde (115169-60-3)

Guidance literature:

With triethylamine; In hexane; dichloromethane; water;

Reference yield: 23.0%

3-(4-trimethylsilylphenyl)cyclobutanecarboxaldehyde (115169-60-3) + tetrabutylammonium (cyano)trihydroborate (43064-96-6) + cis-2,6-dimethylmorpholine (141-91-3,6485-45-6,6485-55-8) → 4-[ trans-3-(4-trimethylsilylphenyl)cyclobutylmethyl]-cis-2,6-dimethylmorpholine (115225-09-7)

Guidance literature:

With hydrogenchloride; silica gel; In methanol; dichloromethane;

upstream raw materials:

oxalyl dichloride

3-(4-trimethylsilylphenyl)cyclobutylmethanol

dimethyl sulfoxide

Downstream raw materials:

4-[ trans-3-(4-trimethylsilylphenyl)cyclobutylmethyl]-cis-2,6-dimethylmorpholine

Refernces