ML355

Base Information

Chemical Name:ML355
CAS No.:1532593-30-8
Molecular Formula:C₂₁H₁₉N₃O₄S₂
Molecular Weight:441.532
Hs Code.:
Mol file:1532593-30-8.mol

Synonyms:N-2-benzothiazolyl-4-[[(2-hydroxy-3-methoxyphenyl)methyl]amino]benzenesulfonamide

Suppliers and Price of ML355

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
ML355
1mg
$ 312.00

TRC
ML355
5mg
$ 130.00

DC Chemicals
ML355 >98%
1 g
$ 1900.00

DC Chemicals
ML355 >98%
100 mg
$ 550.00

Crysdot
ML355 98+%
100mg
$ 1996.00

Crysdot
ML355 98+%
5mg
$ 333.00

Crysdot
ML355 98+%
10mg
$ 475.00

Crysdot
ML355 98+%
25mg
$ 839.00

Crysdot
ML355 98+%
50mg
$ 1426.00

ChemScene
ML355 98.42%
100mg
$ 1250.00

Total 15 raw suppliers

Chemical Property of ML355

Chemical Property:

Melting Point:>182°C (dec.)
Boiling Point:654.5±65.0 °C(Predicted)
PKA:7.58±0.30(Predicted)
Density:1.481±0.06 g/cm3(Predicted)
Storage Temp.:-20°C Freezer, Under inert atmosphere
Solubility.:DMSO (Slightly), Pyridine (Very Slightly)

Purity/Quality:

99%, ^*data from raw suppliers

ML355 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses ML355 is used in the synthesis, structural activity relationship of benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenase.

Technology Process of ML355

There total 8 articles about ML355 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6138-01-8
4-amino-N-(benzo[d]thiazol-2-yl)benzenesulfonamide

: 148-53-8
3-methoxy-2-hydroxybenzaldehyde

: 1532593-30-8
N-2-benzothiazolyl-4-[[(2-hydroxy-3-methoxyphenyl)methyl]amino]benzenesulfonamide

Guidance literature:: 4-amino-N-(benzo[d]thiazol-2-yl)benzenesulfonamide; 3-methoxy-2-hydroxybenzaldehyde; In ethanol; at 90 ℃; for 18h;

With sodium tetrahydroborate; ethanol; at 20 ℃; for 6h;

Reference yield:

: 2516-40-7
2-bromo-1,3-benzothiazole

: 1041600-42-3
4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide

: 1532593-30-8
N-2-benzothiazolyl-4-[[(2-hydroxy-3-methoxyphenyl)methyl]amino]benzenesulfonamide

Guidance literature:: With copper(l) iodide; potassium carbonate; N,N`-dimethylethylenediamine; In 1,4-dioxane; at 80 ℃; Inert atmosphere; Sealed tube;
DOI:10.1021/jm4016476

Reference yield:

: 136-95-8,102337-98-4,84293-42-5
2-amino-benzthiazole

: 1532593-30-8
N-2-benzothiazolyl-4-[[(2-hydroxy-3-methoxyphenyl)methyl]amino]benzenesulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1.1: pyridine / 3.25 h / 20 - 100 °C

2.1: palladium 10% on activated carbon; hydrogen / methanol; ethyl acetate; tetrahydrofuran / 50 °C / 37503.8 Torr

3.1: ethanol / 18 h / 90 °C

3.2: 6 h / 20 °C

With pyridine; palladium 10% on activated carbon; hydrogen; In tetrahydrofuran; methanol; ethanol; ethyl acetate;