Technology Process of 2-phenoxy-4-(4-bromophenyl)thiazole
There total 2 articles about 2-phenoxy-4-(4-bromophenyl)thiazole which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
lithium tetrafluoroborate; 1,10-Phenanthroline; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; palladium diacetate;
at 100 ℃;
for 48h;
regioselective reaction;
Inert atmosphere;
Schlenk technique;
Sealed tube;
DOI:10.1002/ejoc.201402129
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: potassium carbonate / N,N-dimethyl-formamide / 0.5 h / 130 °C / Inert atmosphere; Schlenk technique
1.2: 21 h / 130 °C / Inert atmosphere; Schlenk technique
2.1: palladium diacetate; 1,10-Phenanthroline; lithium tetrafluoroborate; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical / 48 h / 100 °C / Inert atmosphere; Schlenk technique; Sealed tube
With
lithium tetrafluoroborate; 1,10-Phenanthroline; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; palladium diacetate; potassium carbonate;
In
N,N-dimethyl-formamide;
DOI:10.1002/ejoc.201402129
- Guidance literature:
-
With
hydrazine;
In
dimethyl sulfoxide;
at 100 ℃;
for 12h;
Inert atmosphere;
Schlenk technique;
DOI:10.1002/ejoc.201402129
