3-Methyl-2-(4-methylsulfanyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylsulfanyl)-butyramide

Base Information

• Chemical Name: 3-Methyl-2-(4-methylsulfanyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylsulfanyl)-butyramide
• CAS No.: 181702-36-3
• Molecular Formula: C₁₇H₁₉N₅OS₂
• Molecular Weight: 373.503
• Mol file: 181702-36-3.mol

Synonyms:3-Methyl-2-(4-methylsulfanyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylsulfanyl)-butyramide

Chemical Property of 3-Methyl-2-(4-methylsulfanyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylsulfanyl)-butyramide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-Methyl-2-(4-methylsulfanyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylsulfanyl)-butyramide

There total 3 articles about 3-Methyl-2-(4-methylsulfanyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylsulfanyl)-butyramide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

2-(4-Mercapto-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylsulfanyl)-3-methyl-butyramide (181702-33-0) + methyl iodide (74-88-4) → 3-Methyl-2-(4-methylsulfanyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylsulfanyl)-butyramide (181702-36-3)

Guidance literature:

With sodium hydroxide; for 1h; Ambient temperature;

DOI:10.1021/jm960052s

Reference yield:

1-phenylpyrazolo<3,4-d>pyrimidine-4,6(5H,7H)-dithione (6289-02-7) → 3-Methyl-2-(4-methylsulfanyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylsulfanyl)-butyramide (181702-36-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 69 percent / pyridine / 2 h / Ambient temperature

2: 67 percent / aq. NaOH / 1 h / Ambient temperature

With pyridine; sodium hydroxide;

DOI:10.1021/jm960052s

Reference yield:

2-bromo-3-methylbutyramide (7472-46-0) → 3-Methyl-2-(4-methylsulfanyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylsulfanyl)-butyramide (181702-36-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 69 percent / pyridine / 2 h / Ambient temperature

2: 67 percent / aq. NaOH / 1 h / Ambient temperature

With pyridine; sodium hydroxide;

DOI:10.1021/jm960052s

upstream raw materials:

2-(4-Mercapto-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylsulfanyl)-3-methyl-butyramide

methyl iodide

1-phenylpyrazolo<3,4-d>pyrimidine-4,6(5H,7H)-dithione

2-bromo-3-methylbutyramide